Electronic copies of these publications are available for individual, non-commercial use only (†equal contribution)
2018 and in press
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (in press). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse and Neglect.
Humphreys, K. L. (in press). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology.
Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (in press). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science.
Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (in press). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology.
Muscatell, K. A., Brosso, S., & Humphreys, K. L. (2018). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry. doi:10.1038/s41380-018-0259-2
Zeanah, C. H., & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 637-644. doi:0.1016/j.jaac.2018.06.007
Ellwood-Lowe, M. E., Humphreys, K. L., Camacho, C. M., Sacchet, M. D., Ordaz, S. J., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. doi:10.1016/j.dcn.2017.12.005
Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. A. (in press). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development. doi:10.1080/14616734.2018.1499208
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. A. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 329–335.doi:10.1016/j.jaac.2018.02.009. Comment by Dr. Helen Minnis here.
Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. doi:10.1016/j.jad.2018.05.072
Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59, 811-821. doi:10.1111/jcpp.12865
Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2018). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology. doi: 10.1080/15374416.2018.1460847
Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24, 261-276. doi:10.1080/09297049.2016.1264578
Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2018). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology. Available early online. doi.org/10.1007/s10802-018-0443-5.
King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2018). A person-centered approach to early life stress: Neurobiological and symptom correlates. Development and Psychopathology. doi:10.1017/S0954579418000184
LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2018). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology. Available early online. doi: 10.1007/s10802-018-0430-x.
Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. doi:10.1016/j.chiabu.2018.03.016
2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29, 1851-1864.
Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nsx065
†Davis, E. G., †Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D., Kobor, M. S., & Gotlib, I. H. (2017). Diurnal cortisol, accelerated methylation age, and reduced hippocampal volume in adolescent girls. Translational Psychiatry, 7,e1223. doi:10.1038/tp.2017.188. (†equal contribution)
Galán, C. A., & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times.
Flannery, J., Gabard-Durnam, L., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E., Humphreys, K. L., Lumian, D. S., Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166.doi:10.1016/j.dcn.2017.03.006
Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29, 675-684. doi:10.1017/S0954579417000256
VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017). Positive valence bias and parent-child relationship security moderate the association between early institutional care and internalizing problems. Development and Psychopathology, 29, 519-533. doi:10.1017/S0954579417000153
Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children. Insights from the Bucharest Early Intervention Project. Current Opinion in Psychology, 15, 182-188. doi:10.1016/j.copsyc.2017.02.024.
King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroendocrinology, 77, 68-74. doi:10.1016/j.psyneuen.2016.11.024
Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms. Journal of Clinical Child and Adolescent Psychology, 46, 903-914. doi: 10.1080/15374416.2015.1094739
2016
Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. doi:10.1016/j.psychres.2016.09.012.
Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37, 476-485. doi:10.1002/imhj.21592
Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57, 1174-1182. doi:10.1111/jcpp.12607
Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between abuse during childhood and ADHD symptoms in adulthood. Journal of Attention Disorders, 20, 695-703. doi:10.1177/1087054712465337
Silvers, J., Lumian, D., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala-hippocampal-PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36, 6420-6430. doi: 10.1523/JNEUROSCI.0038-16.2016
Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161, 84-93. doi: 10.1002/ajpa.23010
Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L. Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry. doi: 10.0000/jcpp.12578.
Gabard-Durnam, L., Gee, D. G., Goff, B., Flannery, J., Telzer, E. H., Humphreys, K. L., Lumian, D., Fareri, D., Caldera, C. & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36, 4771-4784. doi:10.1523/JNEUROSCI.0598-16.2016
Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44, 1023-1032. doi: 10.1007/s10802-015-0095-7.
Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16, 101-109. doi: 10.1037/emo0000116
2015
Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 977-983. doi: 10.1016/j.jaac.2015.09.010. Comment by Dr. Joan Luby here.
Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D. M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: follow-up of an open, randomised controlled trial. The Lancet Psychiatry, 2, 625-635. doi: 10.1016/S2215-0366(15)00095-4 Comment by Dr. Michael Rutter here. The Lancet editorial coverage here.
Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27, 347-367. doi:10.1017/S0954579415000036
Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter (5HTTLPR) genotype moderates the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36, 409-416. doi:10.1097/DBP.0000000000000171. Comment by Dr. Jay Belsky here.
Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration—exploitation strategy is dependent on early experience. Developmental Psychobiology, 57, 313-321. doi: 10.1002/dev.21293.
Benson, K., Flory, K., Humphreys, K. L., Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis.Clinical Child and Family Psychology Review, 18, 50-76. doi: 10.1007/s10567-014-0177-z
Humphreys, K. L., & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40, 154-170. doi: 10.1038/npp.2014.165.
†Brett, Z. H., †Humphreys, K. L., Smyke, A. T., Gleason, M. M., Nelson, C. A., Zeanah, C. H., Fox, N. A., & Drury, S. S. (2015). 5HTTLPR genotype moderates the longitudinal impact of early caregiving on externalizing behavior. Development and Psychopathology, 27, 7-18. doi:10.1017/S0954579414001266
2014
Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of COMT genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24, 454-457. doi:10.1089/cap.2014.0077
†Gee, D. G., †Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Flannery, J., Shapiro, M., Lumian, D.S., Fareri, D.S., Caldera, C. J., Tottenham, N. (2014). Maternal buffering of human amygdala–prefrontal circuitry during childhood but not adolescence. Psychological Science, 25, 2067-2078.doi:10.1177/0956797614550878
Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19, 145-155. doi:10.1177/1077559514543827
Brett, Z. H., Sheridan, M., Humphreys, K., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2014). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39, 2150-2160. doi:10.1177/0165025414538557
Gabard-Durnam, L., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 Years: a cross-sectional study. NeuroImage, 95, 193-207. doi:10.1016/j.neuroimage.2014.03.038
Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Mental Health Journal, 35, 123-131. doi:10.1002/imhj.21428
Lee, S. S., & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children.Experimental and Clinical Psychopharmacology, 22, 100-109. doi:10.1037/a0035338
2013
Olsavsky, A., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers following early maternal deprivation. Biological Psychiatry, 74, 853-860. doi:10.1016/j.biopsych.2013.05.025
Gee, D. G., Gabard-Durnam, L., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-PFC connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110, 15638–15643. doi:10.1073/pnas.1307893110
†Humphreys, K. L., †Katz, S. J., Lee, S. S., Hammen, C. L., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent-child difficulties in two complementary samples. Journal of Abnormal Psychology, 122, 854-867. doi:10.1037/a0033895
Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70, 740-749.doi:10.1001/jamapsychiatry.2013.1273
Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. doi:10.1016/j.neuroscience.2012.12.010
Telzer, E., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33, 13484-13488. doi: 10.1523/JNEUROSCI.1272-13.2013
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33, 4584-4593. doi:10.1523/JNEUROSCI.3446-12.2013
Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54, 709-715. doi:10.1016/j.paid.2012.11.031
Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race does not emerge until adolescence. Journal of Cognitive Neuroscience, 25, 234-244. doi:10.1162/jocn_a_00311
2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41, 370-377. doi:10.1080/15374416.2012.656557
Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. J., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among combat Veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25, 416-425. doi:10.1002/jts.21729
Tottenham, N., Shapiro, M., Telzer, E., & Humphreys, K. (2012). Amygdala response to mother. Developmental Science, 15, 307-319. doi:10.1111/j.1467-7687.2011.01128.x
Humphreys, K. L., Foley, K., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151.doi:10.1037/a0022644
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16, 267-275. doi:10.1177/1087054710387264
2011
Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25, 15-24. doi:10.1037/a0020298
Castel, A. D., Humphreys, K. L., Lee, S. S., Galvan, A., Balota, D. A. & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47, 1553-1563. doi:10.1037/a0025623
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31, 328-341. doi:10.1016/j.cpr.2011.01.006
Humphreys, K. L., & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. doi:10.1007/s10862-011-9237-6
Feinstein, B. A., Humphreys, K. L., Bovin, M., Marx, B. P., & Resick, P. A. (2011). Victim—offender relationship, peritraumatic responses, and PTSD: A study of female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3,192-200. doi:10.1037/a0021652
2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relation to posttraumatic stress disorder symptomatology. Journal of Interpersonal Violence, 25, 358-373. doi:10.1177/0886260509334412
Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Kaloupek, D. K., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196, 605-611.doi:10.1097/NMD.0b013e318181326d
Heflinger, C. A., & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of the TennCare Medicaid system. Psychological Services, 5, 139-152. doi:10.1037/1541-1559.5.2.139
2018 and in press
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (in press). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse and Neglect.
Humphreys, K. L. (in press). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology.
Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (in press). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science.
Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (in press). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology.
Muscatell, K. A., Brosso, S., & Humphreys, K. L. (2018). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry. doi:10.1038/s41380-018-0259-2
Zeanah, C. H., & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 637-644. doi:0.1016/j.jaac.2018.06.007
Ellwood-Lowe, M. E., Humphreys, K. L., Camacho, C. M., Sacchet, M. D., Ordaz, S. J., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. doi:10.1016/j.dcn.2017.12.005
Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. A. (in press). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development. doi:10.1080/14616734.2018.1499208
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. A. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 329–335.doi:10.1016/j.jaac.2018.02.009. Comment by Dr. Helen Minnis here.
Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. doi:10.1016/j.jad.2018.05.072
Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59, 811-821. doi:10.1111/jcpp.12865
Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2018). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology. doi: 10.1080/15374416.2018.1460847
Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24, 261-276. doi:10.1080/09297049.2016.1264578
Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2018). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology. Available early online. doi.org/10.1007/s10802-018-0443-5.
King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2018). A person-centered approach to early life stress: Neurobiological and symptom correlates. Development and Psychopathology. doi:10.1017/S0954579418000184
LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2018). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology. Available early online. doi: 10.1007/s10802-018-0430-x.
Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. doi:10.1016/j.chiabu.2018.03.016
2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29, 1851-1864.
Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nsx065
†Davis, E. G., †Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D., Kobor, M. S., & Gotlib, I. H. (2017). Diurnal cortisol, accelerated methylation age, and reduced hippocampal volume in adolescent girls. Translational Psychiatry, 7,e1223. doi:10.1038/tp.2017.188. (†equal contribution)
Galán, C. A., & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times.
Flannery, J., Gabard-Durnam, L., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E., Humphreys, K. L., Lumian, D. S., Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166.doi:10.1016/j.dcn.2017.03.006
Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29, 675-684. doi:10.1017/S0954579417000256
VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017). Positive valence bias and parent-child relationship security moderate the association between early institutional care and internalizing problems. Development and Psychopathology, 29, 519-533. doi:10.1017/S0954579417000153
Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children. Insights from the Bucharest Early Intervention Project. Current Opinion in Psychology, 15, 182-188. doi:10.1016/j.copsyc.2017.02.024.
King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroendocrinology, 77, 68-74. doi:10.1016/j.psyneuen.2016.11.024
Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms. Journal of Clinical Child and Adolescent Psychology, 46, 903-914. doi: 10.1080/15374416.2015.1094739
2016
Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. doi:10.1016/j.psychres.2016.09.012.
Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37, 476-485. doi:10.1002/imhj.21592
Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57, 1174-1182. doi:10.1111/jcpp.12607
Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between abuse during childhood and ADHD symptoms in adulthood. Journal of Attention Disorders, 20, 695-703. doi:10.1177/1087054712465337
Silvers, J., Lumian, D., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala-hippocampal-PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36, 6420-6430. doi: 10.1523/JNEUROSCI.0038-16.2016
Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161, 84-93. doi: 10.1002/ajpa.23010
Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L. Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry. doi: 10.0000/jcpp.12578.
Gabard-Durnam, L., Gee, D. G., Goff, B., Flannery, J., Telzer, E. H., Humphreys, K. L., Lumian, D., Fareri, D., Caldera, C. & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36, 4771-4784. doi:10.1523/JNEUROSCI.0598-16.2016
Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44, 1023-1032. doi: 10.1007/s10802-015-0095-7.
Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16, 101-109. doi: 10.1037/emo0000116
2015
Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 977-983. doi: 10.1016/j.jaac.2015.09.010. Comment by Dr. Joan Luby here.
Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D. M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: follow-up of an open, randomised controlled trial. The Lancet Psychiatry, 2, 625-635. doi: 10.1016/S2215-0366(15)00095-4 Comment by Dr. Michael Rutter here. The Lancet editorial coverage here.
Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27, 347-367. doi:10.1017/S0954579415000036
Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter (5HTTLPR) genotype moderates the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36, 409-416. doi:10.1097/DBP.0000000000000171. Comment by Dr. Jay Belsky here.
Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration—exploitation strategy is dependent on early experience. Developmental Psychobiology, 57, 313-321. doi: 10.1002/dev.21293.
Benson, K., Flory, K., Humphreys, K. L., Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis.Clinical Child and Family Psychology Review, 18, 50-76. doi: 10.1007/s10567-014-0177-z
Humphreys, K. L., & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40, 154-170. doi: 10.1038/npp.2014.165.
†Brett, Z. H., †Humphreys, K. L., Smyke, A. T., Gleason, M. M., Nelson, C. A., Zeanah, C. H., Fox, N. A., & Drury, S. S. (2015). 5HTTLPR genotype moderates the longitudinal impact of early caregiving on externalizing behavior. Development and Psychopathology, 27, 7-18. doi:10.1017/S0954579414001266
2014
Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of COMT genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24, 454-457. doi:10.1089/cap.2014.0077
†Gee, D. G., †Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Flannery, J., Shapiro, M., Lumian, D.S., Fareri, D.S., Caldera, C. J., Tottenham, N. (2014). Maternal buffering of human amygdala–prefrontal circuitry during childhood but not adolescence. Psychological Science, 25, 2067-2078.doi:10.1177/0956797614550878
Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19, 145-155. doi:10.1177/1077559514543827
Brett, Z. H., Sheridan, M., Humphreys, K., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2014). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39, 2150-2160. doi:10.1177/0165025414538557
Gabard-Durnam, L., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 Years: a cross-sectional study. NeuroImage, 95, 193-207. doi:10.1016/j.neuroimage.2014.03.038
Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Mental Health Journal, 35, 123-131. doi:10.1002/imhj.21428
Lee, S. S., & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children.Experimental and Clinical Psychopharmacology, 22, 100-109. doi:10.1037/a0035338
2013
Olsavsky, A., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers following early maternal deprivation. Biological Psychiatry, 74, 853-860. doi:10.1016/j.biopsych.2013.05.025
Gee, D. G., Gabard-Durnam, L., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-PFC connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110, 15638–15643. doi:10.1073/pnas.1307893110
†Humphreys, K. L., †Katz, S. J., Lee, S. S., Hammen, C. L., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent-child difficulties in two complementary samples. Journal of Abnormal Psychology, 122, 854-867. doi:10.1037/a0033895
Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70, 740-749.doi:10.1001/jamapsychiatry.2013.1273
Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. doi:10.1016/j.neuroscience.2012.12.010
Telzer, E., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33, 13484-13488. doi: 10.1523/JNEUROSCI.1272-13.2013
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33, 4584-4593. doi:10.1523/JNEUROSCI.3446-12.2013
Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54, 709-715. doi:10.1016/j.paid.2012.11.031
Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race does not emerge until adolescence. Journal of Cognitive Neuroscience, 25, 234-244. doi:10.1162/jocn_a_00311
2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41, 370-377. doi:10.1080/15374416.2012.656557
Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. J., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among combat Veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25, 416-425. doi:10.1002/jts.21729
Tottenham, N., Shapiro, M., Telzer, E., & Humphreys, K. (2012). Amygdala response to mother. Developmental Science, 15, 307-319. doi:10.1111/j.1467-7687.2011.01128.x
Humphreys, K. L., Foley, K., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151.doi:10.1037/a0022644
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16, 267-275. doi:10.1177/1087054710387264
2011
Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25, 15-24. doi:10.1037/a0020298
Castel, A. D., Humphreys, K. L., Lee, S. S., Galvan, A., Balota, D. A. & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47, 1553-1563. doi:10.1037/a0025623
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31, 328-341. doi:10.1016/j.cpr.2011.01.006
Humphreys, K. L., & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. doi:10.1007/s10862-011-9237-6
Feinstein, B. A., Humphreys, K. L., Bovin, M., Marx, B. P., & Resick, P. A. (2011). Victim—offender relationship, peritraumatic responses, and PTSD: A study of female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3,192-200. doi:10.1037/a0021652
2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relation to posttraumatic stress disorder symptomatology. Journal of Interpersonal Violence, 25, 358-373. doi:10.1177/0886260509334412
Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Kaloupek, D. K., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196, 605-611.doi:10.1097/NMD.0b013e318181326d
Heflinger, C. A., & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of the TennCare Medicaid system. Psychological Services, 5, 139-152. doi:10.1037/1541-1559.5.2.139