Accepted and in press
Lynn, A., Humphreys, K. L., & Price, G. R. (online ahead of print). The long arm of adversity: Children’s kindergarten math skills are associated with parents’ experience of childhood adversity. Child Abuse & Neglect, 105561. https://doi.org/10.1016/j.chiabu.2022.105561
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Matsumoto, M., Piersiak, H. A., Letterie, M., & Humphreys, K. L. (online ahead of print). Population-based estimates of associations between child maltreatment types: A meta-analysis. Trauma, Violence, & Abuse. https://doi.org/10.1177/15248380211030502
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Piersiak, H. A., Levi, B. H., & Humphreys, K. L. (online ahead of print). Statutory threshold wording is associated with child maltreatment reporting. Child Maltreatment. https://doi.org/1/15/202210.1177/10775595221092961
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Qian, W., Zhang, C., Piersiak, H. A., Humphreys, K. L., & Mitchell, C. (online ahead of print). Biomarker adoption in developmental science: A data-driven modeling of trends from 90 biomarkers across time. Infant and Child Development. https://doi.org/10.1002/icd.2366
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Robakis, T. K., Roth, M. C., King, L. S., Humphreys, K. L., Ho, M., Zhang, X., Chen, Y., Li, T., Rasgon, N., Watson-Lin, K., Urban, A. E., & Gotlib, I. H. (online ahead of print). Maternal attachment insecurity, maltreatment history, and depressive symptoms are associated with broad DNA methylation signatures in infants. Molecular Psychiatry. https://doi.org/10.1038/s41380-022-01592-w
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Sandre, A., Freeman, C., Renault, R., Humphreys, K. L., & Weinberg, A. (online ahead of print). Maternal symptoms of depression and anxiety during the postpartum period moderate infants’ neural response to emotional faces of their mother and of female strangers. Cognitive, Affective, and Behavioral Neuroscience. https://doi.org/10.3758/s13415-022-01022-y
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Somerville, D., Dore, S., Humphreys, K. L., Verdiglione, N., Zhoi, S., Hamm, R., Fiene, R., Kapp, K., & Levi, B. H. (online ahead of print). State comparison of online mandated reporter trainings. APSAC Advisor.
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Spann, M. N., Wisnowski, J. L., HBCD Phase I Scanning Young Populations Working Group, Smyser, C. D., FIT’NG*, Howell, B., Dean, D. C. (accepted). The science, art and secrets of scanning young children. Biological Psychiatry. *Group authorship member
2022
Barnett, W., Hansen, C. L., Bailes, L. G., & Humphreys, K. L. (2022). Caregiver–child proximity as a dimension of early experience. Development and Psychopathology, 34, 647-665. https://doi.org/10.1017/S0954579421001644
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Bloom, P. A., VanTieghem, M., Gabard-Durnam, L., Gee, D. G., Flannery, J., … Humphreys, K. L., … Tottenham, N. (2022). Age-related change in task-evoked amygdala–prefrontal circuitry: A multiverse approach with an accelerated longitudinal cohort aged 4-22 years. Human Brain Mapping, 43, 3221-3244. https://doi.org/10.1002/hbm.25847.
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Cárdenas, E. F., Kujawa, A., & Humphreys, K. L. (2022). Benevolent childhood experiences and childhood maltreatment history: Examining their roles in depressive symptoms across the peripartum period. Adversity and Resilience Science, 3, 169-179. https://doi.org/10.1007/s42844-022-00062-0
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Cárdenas, E. F., Kujawa, A., Letterie, M., & Humphreys, K. L. (2022). A preliminary test of a brief online intervention for enhancing reflective function and the role of parental depressive symptoms. Journal of Child and Family Studies, 31, 2145-2155. https://doi.org/10.1007/s10826-022-02330-0
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Hendrix, C. L., Werchan, D., Lenninger, C., Ablow, J., Amstadter, A., … Humphreys, K. L., … Thomason, M. E. (2022). Geotemporal analysis of perinatal care changes and maternal mental health: an example from the COVID-19 pandemic. Archives of Women's Mental Health, 25(5), 943-956. https://doi.org/10.1007/s00737-022-01252-6
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Humphreys, K. L., King, L. S., Guyon-Harris, K. L., & Zeanah, C. H. (2022). Caregiver regulation: A modifiable target promoting resilience to early adverse experiences. Psychological Trauma: Theory, Research, Practice, and Policy, 14, S63-S71. https://doi.org/10.1037/tra0001111
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Humphreys, K. L., King, L. S., Guyon-Harris, K. L., Sheridan, M. A., McLaughlin, K. A., Radulescu, A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2022). Foster care leads to sustained cognitive gains following severe early deprivation. Proceedings of the National Academy of Sciences, 119(38). https://doi.org/10.1073/pnas.2119318119
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Jacques, K. P., Feinstein, B. A., Darling, A. K., & Humphreys, K. L. (2022). An Analogue Study Investigating Differential Parenting of Gender Conforming and Nonconforming Boys. Archives of Sexual Behavior, 51(7), 3569-3581. https://doi.org/10.1007/s10508-022-02388-3
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King, L. S., Humphreys, K. L., Cole, D. A. & Gotlib, I. H. (2022). Hair cortisol concentration across the peripartum period: Documenting changes and associations with depressive symptoms and recent adversity. Comprehensive Psychoneuroendocrinology, 22, 100102. https://doi.org/10.1016/j.cpnec.2021.100102
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King, L. S., Humphreys, K. L., Shaw, G. M., Stevenson, D. K., & Gotlib, I. H. (2022). Validation of the Assessment of Parent and Child Adversity (APCA) in mothers and young children. Journal of Clinical Child and Adolescent Psychology, 53, 1-16. https://doi.org/10.1080/15374416.2022.2042696
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Korom, M., †Camacho, M. C., Fillippi, C. A., Licandro, R., Moore, L. A., Dufford, A., Zoillei, L., Graham, A. M., Spann, M., Howell, B., FIT’NG*, Shultz, S., & Scheinost, D. (2022). Dear reviewers: Responses to common reviewer critiques about infant neuroimaging studies. Developmental Cognitive Neuroscience, 53, 101055. https://doi:10.1016/j.dcn.2021.101055. *Group authorship member
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Ojha, A., Miller, J. G., King, L. S., Davis, E. G., Humphreys, K. L., & Gotlib, I. H. (2022). Empathy for others versus for one’s child: Associations with mothers’ brain activation during a social cognitive task and with their toddlers’ functioning. Developmental Psychobiology, 64, e22313. https://doi.org/10.1002/dev.22313
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Pollatou, A., Fillippi, C. A., Aydin, E., Vaughn, K., Thompson, D., Korom, M. … FIT’NG*, Scheinost, D., & Spann, M. (2022). An ode to Fetal, Infant, and Toddler Neuroimaging: Chronicling early clinical to research applications with MRI, and an introduction to an academic society connecting the field. Developmental Cognitive Neuroscience, 54, 101083. https://doi.org/10.1016/j.dcn.2022.101083. *Group authorship member
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Salo, V. C., Pannuto, P., Hedgecock, W., Biri, A., Russo, D. A., Piersiak, H. A., & Humphreys, K. L. (2022). Measuring naturalistic proximity as a window into caregiver–child interaction patterns. Behavior Research Methods, 54, 1580-1592. https://doi.org/10.3758/s13428-021-01681-8
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Salo, V. C., King, L. S., Gotlib, I. H. & Humphreys, K. L. (2022). Infants who experience more adult-initiated conversations have better expressive language in toddlerhood. Infancy, 27(5), 916-936. https://doi.org/10.1111/infa.12487
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Sheridan, M. A., Mukerji, C. E., Wade, M., Humphreys, K. L., Garrisi, K., Goel, S., Patel, K., Fox, N. A., Zeanah, C. H., Nelson, C. A., & McLaughlin, K. A. (2022). Early deprivation alters structural brain development from middle childhood to adolescence. Science Advances, 8(40). https://doi.org/10.1126/sciadv.abn4316.
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Wade, M., Parsons, J., Humphreys, K. L., McLaughlin, K. A., Sheridan, M. A., Zeanah, C. H., Nelson, C. A., & Fox, N. A. (online ahead of print). The Bucharest Early Intervention Project: Adolescent mental health and adaptation following early deprivation. Child Development Perspectives, 16, 157-164. https://doi.org/10.1111/cdep.12462
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Werchan, D. M., Hendrix, C., Ablow, J. C., Amstadler, A. B., Austin, A. C., … Humphreys, K. L., … Brito, N. H. (2022). Behavioral coping phenotypes associated with risk and resilience to adverse outcomes in a national U.S. sample of pregnant and postpartum women during the COVID-19 pandemic. Scientific Reports, 22, 1209. https://doi.org/10.1038/s41598-022-05299-4
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2021
Borchers, L. R., Dennis, E. L., King, L. S., Humphreys, K. L., & Gotlib, I. H. (2021). Prenatal and postnatal depressive symptoms, infant white matter diffusivity, and toddler behavioral problems. Journal of Affective Disorders, 282, 465-471. https://doi.org/10.1016/j.jad.2020.12.075
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Colich, N. L., Sheridan, M. A., Humphreys, K. L., Wade, M., Tibu, F., Nelson, C. A., Zeanah, C. H., Fox, N. A., & McLaughlin, K. A. (2021). Heightened sensitivity to the caregiving environment during adolescence: Implications for recovery following early-life adversity. Journal of Child Psychology and Psychiatry, 62. https://doi.org/10.1111/jcpp.13347
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Glassman, J. R., Humphreys, K. L., Yeung, S., Smith, M., Jauregui, A., Milstein, A., & Sanders, L. M. (2021). Parents’ perspectives on using artificial intelligence to reduce technology interference during early childhood: Cross-sectional online survey. Journal of Medical Internet Research, 23, e19461. https://doi.org/10.2196/19461.
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Guyon-Harris, K. L., Carell, R., DeVlieger, S., Humphreys, K. L., & Huth-Bocks, A. (2021). The emotional tone of child descriptions during pregnancy is associated with later parenting. Journal of Infant Mental Health, 42, 731-739. https://doi.org/10.1002/imhj.21936
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Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Tibu, F., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2021). Early caregiving quality predicts consistency of competent functioning from middle childhood to adolescence following early psychosocial deprivation. Development and Psychopathology, 33, 18-28. https://doi.org/10.1017/S0954579419001500
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Guyon-Harris, K. L., Humphreys, K. L., & Zeanah, C. H. (2021). Adverse caregiving in early life: The trauma and deprivation distinction in young children. Infant Mental Health Journal, 42, 87-95. https://doi.org/10.1002/imhj.21892
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Humphreys, K. L., Piersiak, H. A., Panlilio, C. C., Lehman, E. B., Verdiglione, N., Dore, S., & Levi, B. (2021). A randomized controlled trial of a child abuse mandated reporter training: Knowledge and attitudes. Child Abuse & Neglect, 117, 105033. https://doi.org/10.1016/j.chiabu.2021.105033
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King, L. S., Feddoes, D. E., Kirschenbaum, J. S., Humphreys, K. L., & Gotlib, I. H. (2021). Pregnancy during the pandemic: The impact of COVID-19-related stress on risk for prenatal depression. Psychological Medicine, 1-11. https://doi.org/10.1017/S003329172100132X
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King, L. S., Camacho, M. C., Montez, D. F., Humphreys, K. L., & Gotlib, I. H. (2021). Naturalistic language input is associated with resting-state functional connectivity in infancy. Journal of Neuroscience, 41, 424-434. https://doi.org/10.1523/JNEUROSCI.0779-20.2020
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King, L. S., Querdasi, F. R., Humphreys, K. L., & Gotlib, I. H. (2021). Dimensions of the language environment in infancy and symptoms of psychopathology in toddlerhood. Developmental Science, 24, e13082. https://doi.org/10.1111/desc.13082
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King, L. S., Salo, V. C., Kujawa, A., & Humphreys, K. L. (2021). Advancing the RDoC initiative through the assessment of caregiver social processes. Development and Psychopathology, 33, 1645-1664. https://doi.org/10.1017/S095457942100064X
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MacCormack, J. K., Armstrong-Carter, E., Humphreys, K. L., & Muscatell, K. A. (2021). Neurophysiological contributors to advantageous risk-taking: An experimental psychopharmacological investigation. Social Cognitive and Affective Neuroscience, 16, 926-936. https://doi.org/10.1093/scan/nsab047
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McLaughlin, K. A., Sheridan, M. A, Humphreys, K. L., Belsky, J., & Ellis, B. J. (2021). The value of dimensional models of early experience: Thinking clearly about concepts and categories. Perspectives on Psychological Science, 16, 1463-1472. https://doi.org/10.1177/1745691621992346.
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Roth, M. C., Humphreys, K. L., King, L. S., Gotlib, I. H., & Robackis, T. K. (2021). Breastfeeding difficulties predict mother–infant bonding from birth to age six months. Maternal and Child Health Journal, 25, 777-785. https://doi.org/10.1007/s10995-020-03036-9
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Roth, M. C., Humphreys, K. L., King, L. S., Mondal, S., Gotlib, I. H., & Robackis, T. K. (2021). Attachment security in pregnancy mediates the association between maternal childhood maltreatment and emotional and behavioral problems in offspring. Child Psychiatry & Human Development., 52, 966-977. https://doi.org/10.1007/s10578-020-01073-7
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Sun, Y., Gao, K., Wu, Z., Lei, Z., Wei, Y., … Humphreys, K. L., … & Wang, L. (2021). Multi-site infant brain segmentation algorithms: The iSeg-2019 challenge. IEEE Transactions on Medical Imaging, 40, 1363-1376. doi:10.1109/TMI.2021.3055428
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VanTieghem, M., Korom, M., Flannery, J., Choy, T., Caldera, C., Humphreys, K. L., Gabard-Durnam, L., Goff, B., Gee, D. G., Telzer, E. H., Shapiro, M., Louie, J. Y., Fareri, D. S., Bolger, N., & Tottenham, N. (2021). Longitudinal changes in amygdala, hippocampus, and cortisol development following early caregiving adversity. Developmental Cognitive Neuroscience, 48, 100916. https://doi.org/10.1016/j.dcn.2021.100916
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2020
Callaghan, B. L., Fields, A., Gee, D. G., Gabard-Durnam, L., Caldera, C., Humphreys, K. L., Goff, B., Flannery, J., Telzer, E. H., Shapiro, M., & Tottenham, N. (2020). Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, 32, 309-328. https://doi.org/10.1017/S0954579419000087
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Camacho, M. C., King, L. S., Ojha, A., Garcia, C. M., Sisk, L. M., Cichocki, A. C., Humphreys, K. L., & Gotlib, I. H. (2020). Cerebral blood flow in 5- to 8-month-olds: Regional tissue maturity is associated with infant affect. Developmental Science, 23, 5, e12928. https://doi.org/10.1111/desc.12928
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Cárdenas E. F., Kujawa, A., & Humphreys, K. L. (2020). Neurobiological changes during the peripartum period: Implications for health and behavior. Social Cognitive and Affective Neuroscience, 15, 1097-1110. https://doi.org/10.1093/scan/nsz091
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Castellanos, R., Spinel, M. Y., Phan, V., Orengo-Aguayo, R., Humphreys, K. L., & Flory, K. (2020). A systematic review and meta-analysis of cultural adaptations of mindfulness-based interventions for Hispanic populations. Mindfulness,11, 317-332. https://doi.org/10.1007/s12671-019-01210-x
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Gotlib, I. H., Goodman, S. H., & Humphreys, K. L. (2020). Studying the intergenerational transmission of risk for depression: Current status and future directions.C Current Directions in Psychological Science, 29, 174-179. https://doi.org/10.1177/0963721420901590
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Humphreys, K. L. (2020). Child maltreatment recurrence points to urgent need to improve systems for identification and prevention. Journal of the American Academy of Child and Adolescent Psychiatry, 59, 1102-1104. https://doi.org/10.1016/j.jaac.2020.07.005
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Humphreys, K. L., Camacho, M. C., Roth, M. C., & Estes, E. C. (2020). Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants. Developmental Cognitive Neuroscience, 46, 100877. https://doi.org/10.1016/j.dcn.2020.100877
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Humphreys, K. L., Guyon-Harris, K. L., Tibu, F., Wade, M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2020). Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16. Journal of Consulting and Clinical Psychology, 88, 1079-1090. https://dx.doi.org/10.1037/ccp0000613
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Humphreys, K. L., †LeMoult, J., Wear, J. G., Piersiak, H. A., Lee, A., & Gotlib, I. H. (2020). Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse & Neglect, 102, 104361. https://doi.org/10.1016/j.chiabu.2020.104361 **Selected as the 2020 Article of the Year in Child Abuse & Neglect**
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Humphreys, K. L., Machlin, L. S., Guyon-Harris, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2020). Psychosocial deprivation and receptive language: A two sample study. Journal of Neurodevelopmental Disorders, 12, 36. https://doi.org/10.1186/s11689-020-09341-2
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Humphreys, K. L., Myint, M. T., & Zeanah, C. H. (2020). Increased risk for family violence during the COVID-19 pandemic. Pediatrics, 146, e20200982. https://doi.org/10.1542/peds.2020-0982
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Humphreys, K. L., Sisk, L. M., Mancszak, E. M., Lin, J., & Gotlib, I. H. (2020). Depressive symptoms predict change in telomere length and mitochondrial DNA copy number across adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59, 1364-1370. https://doi.org/10.1016/j.jaac.2019.09.031
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Humphreys, K. L. & Salo, V. C. (2020). Expectable environments in early life. Current Opinion in Behavioral Sciences, 36, 115-119. https://doi.org/10.1016/j.cobeha.2020.09.004
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King, L. S., Dennis, E. L., Humphreys, K. L., Thompson, P. M., & Gotlib, I. H. (2020). Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls. Developmental Cognitive Neuroscience, 44, 100796. https://doi.org/10.1016/j.dcn.2020.100796
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LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J., Ip, E., & Gotlib, I. H. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59, 842-855. https://doi.org/10.1016/j.jaac.2019.10.011
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Miller, J. G., Ho, T. C., Humphreys, K. L., King, L. S., Foland-Ross, L. C., Colich, N. L., Ordaz, S. J., Lin, J., & Gotlib, I. H. (2020). Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation. Cerebral Cortex, 30, 4269-4280. https://doi.org/10.1093/cercor/bhaa057
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Moore, S. R., Humphreys, K. L., Colich, N. L., Davis, E. G., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., & Gotlib, I. H. (2020). Distinctions between sex and time in patterns of DNA methylation across puberty. BMC Genomics, 21, 389. https://doi.org/10.1186/s12864-020-06789-3
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Muscatell, K. A., Brosso, S. N., & Humphreys, K. L. (2020). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry, 25, 2189-2199. https://doi.org/10.1038/s41380-018-0259-2
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Robakis, T. K., Zhang, S., Rasgon, N. L., Li, T., Wang, T., Roth, M. C., Humphreys, K. L., Gotlib, I. H., Ho, M., Khechaduri, A., Watson, K., Roat-Shumway, S., Budhan, V. V., David, K. N., Crowe, S. D., Williams, K. E., & Urban, A. E. (2020). Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Translational Psychiatry, 10, 48. https://doi.org/10.1038/s41398-020-0703-3
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Salo, V. C., Schunck, S. J., & Humphreys, K. L. (2020). Depressive symptoms in parents are associated with reduced empathy toward their young children. PLoS ONE, 15, e0230636. https://doi.org/10.1371/journal.pone.0230636
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Zeanah, C. H. & Humphreys, K. L. (2020). Global prevalence of institutional care for children: A call for change. The Lancet Child & Adolescent Health, 4, 343-344. https://doi.org/10.1016/S2352-4642(20)30055-9
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2019
Callaghan, B. L., Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: An examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 664-671. https://doi.org/10.1016/j.bpsc.2019.02.001
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Dennis, E. L., Humphreys, K. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Irritability and brain volume in adolescents: Cross-sectional and longitudinal associations. Social Cognitive and Affective Neuroscience, 14, 687-698. https://doi.org/10.1093/scan/nsz053
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Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development, 21, 95-110. https://doi.org/10.1080/14616734.2018.1499208
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Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse & Neglect, 88, 96-106. https://doi.org/10.1016/j.chiabu.2018.11.005
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Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Gleason, M. M., Nelson, C. A., Fox, N. A., Zeanah, C. H. (2019). Disinhibited social engagement disorder in early childhood predicts reduced competence in early adolescence. Journal of Abnormal Child Psychology, 47, 1735-1745. https://doi.org/10.1007/s10802-019-00547-0
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Humphreys, K. L., †Moore, S. R., †Davis, E. G., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2019). DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: A prospective analysis. Translational Psychiatry, 9, 245. https://doi.org/10.1038/s41398-019-0582-7
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Humphreys, K. L. (2019). Early caregiving intervention holds promise for long-term improvements in neural function following adversity. Biological Psychiatry, 85, e15-e16. https://doi.org/10.1016/j.biopsych.2018.12.005
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Humphreys, K. L. (2019). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology, 48, 166-178. https://doi.org/10.1080/15374416.2018.1534209
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Humphreys, K. L. (2019). Understanding the link between early adversity and disease – Stress, immunity, and prevention. Brain, Behavior, and Immunity, 78, 1-2. https://doi.org/10.1016/j.bbi.2018.12.019
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Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (2019). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science, 22, e12775. https://doi.org/10.1111/desc.12775
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Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology, 47, 421-432. https://doi.org/10.1007/s10802-018-0443-5
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Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (2019). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, 31, 1477-1487. https://doi.org/10.1017/S0954579418001050
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Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2019). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology, 48, 781-789. https://doi.org/10.1080/15374416.2018.1460847
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King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2019). A person-centered approach to the assessment of early life stress: Associations with the volume of stress-sensitive brain regions in early adolescence. Development and Psychopathology, 31, 643-655. https://doi.org/10.1017/S0954579418000184
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King, L. S., Humphreys, K. L., & Gotlib, I. H. (2019). The neglect–enrichment continuum: Characterizing variation in early caregiving environments. Developmental Review, 51, 109-122. https://doi.org/10.1016/j.dr.2019.01.001
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Kircanski, K., Sisk, L. M., Ho, T. C., Humphreys, K. L., King, L. S., Colich, N. L., Ordaz, S. J., & Gotlib, I. H. (2019). Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. Development and Psychopathology, 31, 1011-1022. https://doi.org/10.1017/S0954579419000555
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LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2019). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology, 47, 199-207. https://doi.org/10.1007/s10802-018-0430-x
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2018
Ellwood-Lowe, M. E., Humphreys, K. L., Ordaz, S. J., Camacho, M. C., Sacchet, M. D., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. https://doi.org/10.1016/j.dcn.2017.12.005
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Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 329-335. https://doi.org/10.1016/j.jaac.2018.02.009
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Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. https://doi.org/10.1016/j.jad.2018.05.072
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Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59, 811-821. https://doi.org/10.1111/jcpp.12865
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Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24, 261-276. https://doi.org/10.1080/09297049.2016.1264578
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Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. https://doi.org/10.1016/j.chiabu.2018.03.016
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Zeanah, C. H. & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 637-644. https://doi.org/10.1016/j.jaac.2018.06.007
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2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29, 1851-1864. https://doi.org/10.1017/S0954579417001444
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Davis, E. G., †Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2017). Accelerated DNA methylation age in adolescent girls: Associations with elevated diurnal cortisol and reduced hippocampal volume. Translational Psychiatry, 7, e1223. https://doi.org/10.1038/tp.2017.188
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Flannery, J. E., Gabard-Durnam, L. J., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E. H., Humphreys, K. L., Lumian, D. S., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166. https://doi.org/10.1016/j.dcn.2017.03.006
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Galán, C. A. & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times, 34, 1-3.
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Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience, 12, 1460-1469. https://doi.org/10.1093/scan/nsx065
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Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29, 675-684. https://doi.org/10.1017/S0954579417000256
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Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms.
Journal of Clinical Child and Adolescent Psychology, 46, 903-914. https://doi.org/10.1080/15374416.2015.1094739
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King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A. N., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroenddocrinology, 77, 68-74. https://doi.org/10.1016/j.psyneuen.2016.11.024
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VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017). Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and Psychopathology, 29, 519-533. https://doi.org/10.1017/S0954579417000153
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Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children: Insights from the Bucharest Early Intervention Project.
Current Opinion in Psychology, 15, 182-188. https://doi.org/10.1016/j.copsyc.2017.02.024
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2016
Gabard-Durnam, L. J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K. L., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36, 4771-4784. https://doi.org/10.1523/JNEUROSCI.0598-16.2016
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Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37, 476-485. https://doi.org/10.1002/imhj.21592
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Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L., Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57, 1135-1144. https://doi.org/10.1111/jcpp.12578
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Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. https://doi.org/10.1016/j.psychres.2016.09.023
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Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44, 1023-1032. https://doi.org/10.1007/s10802-015-0095-7
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Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57, 1174-1182. https://doi.org/10.1111/jcpp.12607
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Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16, 101-109. https://doi.org/10.1037/emo0000116
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Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161, 84-93. https://doi.org/10.1002/ajpa.23010
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Silvers, J. A., Lumian, D. S., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D. S., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala–hippocampal PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36, 6420-6430. https://doi.org/10.1523/JNEUROSCI.0038-16.2016
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Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. Journal of Attention Disorders, 20, 695-703. https://doi.org/10.1177/1087054712465337
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2015
Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis. Clinical Child and Family Psychology Review, 18, 50-76. https://doi.org/10.1007/s10567-014-0177-z
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Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27, 347-367. https://doi.org/10.1007/s10567-014-0177-z
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Brett, Z. H., †Humphreys, K. L., Smyke, A. T., Gleason, M., Nelson, C. A., Zeanah, C. H., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter linked polymorphic region (5-HTTLPR) genotype moderates the longitudinal impact of early caregiving on externalizing behavior. Development and Psychopathology, 27, 7-18. https://doi.org/10.1017/S0954579414001266
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Brett, Z. H., Sheridan, M., Humphreys, K. L., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2015). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39, 150-160. https://doi.org/10.1177/0165025414538557
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Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter genotype (5HTTLPR) moderates the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36, 409-416. https://doi.org/10.1097/DBP.0000000000000171
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Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: Follow-up of an open, randomized controlled trial. The Lancet Psychiatry, 2, 625-634. https://doi.org/10.1016/S2215-0366(15)00095-4
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Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration-exploitation strategy is dependent on early experience. Developmental Psychobiology, 57, 313-321. https://doi.org/10.1002/dev.21293
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Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 977-983. https://doi.org/10.1016/j.jaac.2015.09.010 **Received the Norbert and Charlotte Rieger Award for Scientific Achievement from the American Academy of Child and Adolescent Psychiatry (Journal of the American Academy of Child and Adolescent Psychiatry outstanding paper of the year)**
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Humphreys, K. L. & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40, 154-170. https://doi.org/10.1038/npp.2014.165
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Telzer, E. H., Flannery, J., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. G., & Tottenham, N. (2015). "The cooties effect": Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 27, 1685-1696. https://doi.org/10.1162/jocn_a_00813
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2014
Gabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 years: A cross-sectional study. NeuroImage, 95, 193-207. https://doi.org/10.1016/j.neuroimage.2014.03.038
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Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala-prefrontal circuitry during childhood but not during adolescence. Psychological Science, 25, 2067-2078. https://doi.org/10.1177/0956797614550878
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Gee, D. G., Gabard-Durnam, L. J., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E. H., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110, 15638-15643. https://doi.org/10.1073/pnas.1307893110
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Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of Catechol-O-methyltransferase genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24, , 454-457. https://doi.org/10.1089/cap.2014.0077
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Lee, S. S. & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children. Experimental and Clinical Psychopharmacology, 22, 100-109. https://doi.org/10.1037/a0035338
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Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19, 145-155. https://doi.org/10.1177/1077559514543827
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Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing.
Infant Mental Health Journal, 35, 123-131. https://doi.org/10.1002/imhj.21428
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2013
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33, 4584-4593. https://doi.org/10.1523/JNEUROSCI.3446-12.2013
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Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. https://doi.org/10.1016/j.neuroscience.2012.12.010
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Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70, 740-749. https://doi.org/10.1001/jamapsychiatry.2013.1273
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Humphreys, K. L., Katz, S. J., Lee, S. S., Hammen, C., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent–child difficulties in two complementary samples. Journal of Abnormal Psychology, 122, 854-867. https://doi.org/10.1037/a0033895
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Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54, 709-715. https://doi.org/10.1016/j.paid.2012.11.031
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Olsavsky, A. K., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74, 853-860. https://doi.org/10.1016/j.biopsych.2013.05.025
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Telzer, E. H., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33, 13484-13488. https://doi.org/10.1523/JNEUROSCI.1272-13.2013
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Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race is not present in childhood but emerges over adolescence. Journal of Cognitive Neuroscience, 25, 234-244. https://doi.org/10.1162/jocn_a_00311
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2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41, 370-377. https://doi.org/10.1080/15374416.2012.656557
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Humphreys, K. L., Foley, K. M., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151. https://doi.org/10.1037/a0022644
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Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorder, 16, 267-275. https://doi.org/10.1177/1087054710387264
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Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. G., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among Vietnam combat veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25, 416-425. https://doi.org/10.1002/jts.21729
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Tottenham, N., Shapiro, M., Telzer, E. H., & Humphreys, K. L. (2012). Amygdala response to mother. Developmental Science, 15, 307-319. https://doi.org/10.1111/j.1467-7687.2011.01128.x
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2011
Castel, A. D., Humphreys, K. L., Lee, S. S., Galván, A., Balota, D. A., & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47, 1553-1564. https://doi.org/10.1037/a0025623
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Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25, 15-24. https://doi.org/10.1037/a0020298
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Feinstein, B. A., Humphreys, K. L., Bovin, M. J., Marx, B. P., & Resick, P. A. (2011). Victim-offender relationship status moderates the relationships of peritraumatic emotional responses, active resistance, and posttraumatic stress symptomatology in female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3, 192-200. https://doi.org/10.1037/a0021652
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Humphreys, K. L. & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. https://doi.org/10.1007/s10862-011-9237-6
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Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31, 328-341. https://doi.org/10.1016/j.cpr.2011.01.006
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2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relationship to posttraumatic stress symptomatology. Journal of Interpersonal Violence, 25, 358-373. https://doi.org/10.1177/0886260509334412
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Heflinger, C. A. & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of one state’s public service system. Psychological Services, 5, 139-152. https://doi.org/10.1037/1541-1559.5.2.139
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Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Grove, W. M., Kaloupek, D. G., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196, 605-611. https://doi.org/10.1097/NMD.0b013e318181326d
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Lynn, A., Humphreys, K. L., & Price, G. R. (online ahead of print). The long arm of adversity: Children’s kindergarten math skills are associated with parents’ experience of childhood adversity. Child Abuse & Neglect, 105561. https://doi.org/10.1016/j.chiabu.2022.105561
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Matsumoto, M., Piersiak, H. A., Letterie, M., & Humphreys, K. L. (online ahead of print). Population-based estimates of associations between child maltreatment types: A meta-analysis. Trauma, Violence, & Abuse. https://doi.org/10.1177/15248380211030502
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Piersiak, H. A., Levi, B. H., & Humphreys, K. L. (online ahead of print). Statutory threshold wording is associated with child maltreatment reporting. Child Maltreatment. https://doi.org/1/15/202210.1177/10775595221092961
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Qian, W., Zhang, C., Piersiak, H. A., Humphreys, K. L., & Mitchell, C. (online ahead of print). Biomarker adoption in developmental science: A data-driven modeling of trends from 90 biomarkers across time. Infant and Child Development. https://doi.org/10.1002/icd.2366
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Robakis, T. K., Roth, M. C., King, L. S., Humphreys, K. L., Ho, M., Zhang, X., Chen, Y., Li, T., Rasgon, N., Watson-Lin, K., Urban, A. E., & Gotlib, I. H. (online ahead of print). Maternal attachment insecurity, maltreatment history, and depressive symptoms are associated with broad DNA methylation signatures in infants. Molecular Psychiatry. https://doi.org/10.1038/s41380-022-01592-w
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Sandre, A., Freeman, C., Renault, R., Humphreys, K. L., & Weinberg, A. (online ahead of print). Maternal symptoms of depression and anxiety during the postpartum period moderate infants’ neural response to emotional faces of their mother and of female strangers. Cognitive, Affective, and Behavioral Neuroscience. https://doi.org/10.3758/s13415-022-01022-y
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Somerville, D., Dore, S., Humphreys, K. L., Verdiglione, N., Zhoi, S., Hamm, R., Fiene, R., Kapp, K., & Levi, B. H. (online ahead of print). State comparison of online mandated reporter trainings. APSAC Advisor.
Spann, M. N., Wisnowski, J. L., HBCD Phase I Scanning Young Populations Working Group, Smyser, C. D., FIT’NG*, Howell, B., Dean, D. C. (accepted). The science, art and secrets of scanning young children. Biological Psychiatry. *Group authorship member
2022
Barnett, W., Hansen, C. L., Bailes, L. G., & Humphreys, K. L. (2022). Caregiver–child proximity as a dimension of early experience. Development and Psychopathology, 34, 647-665. https://doi.org/10.1017/S0954579421001644
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Bloom, P. A., VanTieghem, M., Gabard-Durnam, L., Gee, D. G., Flannery, J., … Humphreys, K. L., … Tottenham, N. (2022). Age-related change in task-evoked amygdala–prefrontal circuitry: A multiverse approach with an accelerated longitudinal cohort aged 4-22 years. Human Brain Mapping, 43, 3221-3244. https://doi.org/10.1002/hbm.25847.
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Cárdenas, E. F., Kujawa, A., & Humphreys, K. L. (2022). Benevolent childhood experiences and childhood maltreatment history: Examining their roles in depressive symptoms across the peripartum period. Adversity and Resilience Science, 3, 169-179. https://doi.org/10.1007/s42844-022-00062-0
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Cárdenas, E. F., Kujawa, A., Letterie, M., & Humphreys, K. L. (2022). A preliminary test of a brief online intervention for enhancing reflective function and the role of parental depressive symptoms. Journal of Child and Family Studies, 31, 2145-2155. https://doi.org/10.1007/s10826-022-02330-0
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Hendrix, C. L., Werchan, D., Lenninger, C., Ablow, J., Amstadter, A., … Humphreys, K. L., … Thomason, M. E. (2022). Geotemporal analysis of perinatal care changes and maternal mental health: an example from the COVID-19 pandemic. Archives of Women's Mental Health, 25(5), 943-956. https://doi.org/10.1007/s00737-022-01252-6
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Humphreys, K. L., King, L. S., Guyon-Harris, K. L., & Zeanah, C. H. (2022). Caregiver regulation: A modifiable target promoting resilience to early adverse experiences. Psychological Trauma: Theory, Research, Practice, and Policy, 14, S63-S71. https://doi.org/10.1037/tra0001111
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Humphreys, K. L., King, L. S., Guyon-Harris, K. L., Sheridan, M. A., McLaughlin, K. A., Radulescu, A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2022). Foster care leads to sustained cognitive gains following severe early deprivation. Proceedings of the National Academy of Sciences, 119(38). https://doi.org/10.1073/pnas.2119318119
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Jacques, K. P., Feinstein, B. A., Darling, A. K., & Humphreys, K. L. (2022). An Analogue Study Investigating Differential Parenting of Gender Conforming and Nonconforming Boys. Archives of Sexual Behavior, 51(7), 3569-3581. https://doi.org/10.1007/s10508-022-02388-3
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King, L. S., Humphreys, K. L., Cole, D. A. & Gotlib, I. H. (2022). Hair cortisol concentration across the peripartum period: Documenting changes and associations with depressive symptoms and recent adversity. Comprehensive Psychoneuroendocrinology, 22, 100102. https://doi.org/10.1016/j.cpnec.2021.100102
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King, L. S., Humphreys, K. L., Shaw, G. M., Stevenson, D. K., & Gotlib, I. H. (2022). Validation of the Assessment of Parent and Child Adversity (APCA) in mothers and young children. Journal of Clinical Child and Adolescent Psychology, 53, 1-16. https://doi.org/10.1080/15374416.2022.2042696
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Korom, M., †Camacho, M. C., Fillippi, C. A., Licandro, R., Moore, L. A., Dufford, A., Zoillei, L., Graham, A. M., Spann, M., Howell, B., FIT’NG*, Shultz, S., & Scheinost, D. (2022). Dear reviewers: Responses to common reviewer critiques about infant neuroimaging studies. Developmental Cognitive Neuroscience, 53, 101055. https://doi:10.1016/j.dcn.2021.101055. *Group authorship member
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Ojha, A., Miller, J. G., King, L. S., Davis, E. G., Humphreys, K. L., & Gotlib, I. H. (2022). Empathy for others versus for one’s child: Associations with mothers’ brain activation during a social cognitive task and with their toddlers’ functioning. Developmental Psychobiology, 64, e22313. https://doi.org/10.1002/dev.22313
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Pollatou, A., Fillippi, C. A., Aydin, E., Vaughn, K., Thompson, D., Korom, M. … FIT’NG*, Scheinost, D., & Spann, M. (2022). An ode to Fetal, Infant, and Toddler Neuroimaging: Chronicling early clinical to research applications with MRI, and an introduction to an academic society connecting the field. Developmental Cognitive Neuroscience, 54, 101083. https://doi.org/10.1016/j.dcn.2022.101083. *Group authorship member
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Salo, V. C., Pannuto, P., Hedgecock, W., Biri, A., Russo, D. A., Piersiak, H. A., & Humphreys, K. L. (2022). Measuring naturalistic proximity as a window into caregiver–child interaction patterns. Behavior Research Methods, 54, 1580-1592. https://doi.org/10.3758/s13428-021-01681-8
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Salo, V. C., King, L. S., Gotlib, I. H. & Humphreys, K. L. (2022). Infants who experience more adult-initiated conversations have better expressive language in toddlerhood. Infancy, 27(5), 916-936. https://doi.org/10.1111/infa.12487
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Sheridan, M. A., Mukerji, C. E., Wade, M., Humphreys, K. L., Garrisi, K., Goel, S., Patel, K., Fox, N. A., Zeanah, C. H., Nelson, C. A., & McLaughlin, K. A. (2022). Early deprivation alters structural brain development from middle childhood to adolescence. Science Advances, 8(40). https://doi.org/10.1126/sciadv.abn4316.
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Wade, M., Parsons, J., Humphreys, K. L., McLaughlin, K. A., Sheridan, M. A., Zeanah, C. H., Nelson, C. A., & Fox, N. A. (online ahead of print). The Bucharest Early Intervention Project: Adolescent mental health and adaptation following early deprivation. Child Development Perspectives, 16, 157-164. https://doi.org/10.1111/cdep.12462
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Werchan, D. M., Hendrix, C., Ablow, J. C., Amstadler, A. B., Austin, A. C., … Humphreys, K. L., … Brito, N. H. (2022). Behavioral coping phenotypes associated with risk and resilience to adverse outcomes in a national U.S. sample of pregnant and postpartum women during the COVID-19 pandemic. Scientific Reports, 22, 1209. https://doi.org/10.1038/s41598-022-05299-4
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2021
Borchers, L. R., Dennis, E. L., King, L. S., Humphreys, K. L., & Gotlib, I. H. (2021). Prenatal and postnatal depressive symptoms, infant white matter diffusivity, and toddler behavioral problems. Journal of Affective Disorders, 282, 465-471. https://doi.org/10.1016/j.jad.2020.12.075
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Colich, N. L., Sheridan, M. A., Humphreys, K. L., Wade, M., Tibu, F., Nelson, C. A., Zeanah, C. H., Fox, N. A., & McLaughlin, K. A. (2021). Heightened sensitivity to the caregiving environment during adolescence: Implications for recovery following early-life adversity. Journal of Child Psychology and Psychiatry, 62. https://doi.org/10.1111/jcpp.13347
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Glassman, J. R., Humphreys, K. L., Yeung, S., Smith, M., Jauregui, A., Milstein, A., & Sanders, L. M. (2021). Parents’ perspectives on using artificial intelligence to reduce technology interference during early childhood: Cross-sectional online survey. Journal of Medical Internet Research, 23, e19461. https://doi.org/10.2196/19461.
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Guyon-Harris, K. L., Carell, R., DeVlieger, S., Humphreys, K. L., & Huth-Bocks, A. (2021). The emotional tone of child descriptions during pregnancy is associated with later parenting. Journal of Infant Mental Health, 42, 731-739. https://doi.org/10.1002/imhj.21936
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Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Tibu, F., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2021). Early caregiving quality predicts consistency of competent functioning from middle childhood to adolescence following early psychosocial deprivation. Development and Psychopathology, 33, 18-28. https://doi.org/10.1017/S0954579419001500
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Guyon-Harris, K. L., Humphreys, K. L., & Zeanah, C. H. (2021). Adverse caregiving in early life: The trauma and deprivation distinction in young children. Infant Mental Health Journal, 42, 87-95. https://doi.org/10.1002/imhj.21892
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Humphreys, K. L., Piersiak, H. A., Panlilio, C. C., Lehman, E. B., Verdiglione, N., Dore, S., & Levi, B. (2021). A randomized controlled trial of a child abuse mandated reporter training: Knowledge and attitudes. Child Abuse & Neglect, 117, 105033. https://doi.org/10.1016/j.chiabu.2021.105033
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King, L. S., Feddoes, D. E., Kirschenbaum, J. S., Humphreys, K. L., & Gotlib, I. H. (2021). Pregnancy during the pandemic: The impact of COVID-19-related stress on risk for prenatal depression. Psychological Medicine, 1-11. https://doi.org/10.1017/S003329172100132X
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King, L. S., Camacho, M. C., Montez, D. F., Humphreys, K. L., & Gotlib, I. H. (2021). Naturalistic language input is associated with resting-state functional connectivity in infancy. Journal of Neuroscience, 41, 424-434. https://doi.org/10.1523/JNEUROSCI.0779-20.2020
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King, L. S., Querdasi, F. R., Humphreys, K. L., & Gotlib, I. H. (2021). Dimensions of the language environment in infancy and symptoms of psychopathology in toddlerhood. Developmental Science, 24, e13082. https://doi.org/10.1111/desc.13082
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King, L. S., Salo, V. C., Kujawa, A., & Humphreys, K. L. (2021). Advancing the RDoC initiative through the assessment of caregiver social processes. Development and Psychopathology, 33, 1645-1664. https://doi.org/10.1017/S095457942100064X
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MacCormack, J. K., Armstrong-Carter, E., Humphreys, K. L., & Muscatell, K. A. (2021). Neurophysiological contributors to advantageous risk-taking: An experimental psychopharmacological investigation. Social Cognitive and Affective Neuroscience, 16, 926-936. https://doi.org/10.1093/scan/nsab047
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McLaughlin, K. A., Sheridan, M. A, Humphreys, K. L., Belsky, J., & Ellis, B. J. (2021). The value of dimensional models of early experience: Thinking clearly about concepts and categories. Perspectives on Psychological Science, 16, 1463-1472. https://doi.org/10.1177/1745691621992346.
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Roth, M. C., Humphreys, K. L., King, L. S., Gotlib, I. H., & Robackis, T. K. (2021). Breastfeeding difficulties predict mother–infant bonding from birth to age six months. Maternal and Child Health Journal, 25, 777-785. https://doi.org/10.1007/s10995-020-03036-9
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Roth, M. C., Humphreys, K. L., King, L. S., Mondal, S., Gotlib, I. H., & Robackis, T. K. (2021). Attachment security in pregnancy mediates the association between maternal childhood maltreatment and emotional and behavioral problems in offspring. Child Psychiatry & Human Development., 52, 966-977. https://doi.org/10.1007/s10578-020-01073-7
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Sun, Y., Gao, K., Wu, Z., Lei, Z., Wei, Y., … Humphreys, K. L., … & Wang, L. (2021). Multi-site infant brain segmentation algorithms: The iSeg-2019 challenge. IEEE Transactions on Medical Imaging, 40, 1363-1376. doi:10.1109/TMI.2021.3055428
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VanTieghem, M., Korom, M., Flannery, J., Choy, T., Caldera, C., Humphreys, K. L., Gabard-Durnam, L., Goff, B., Gee, D. G., Telzer, E. H., Shapiro, M., Louie, J. Y., Fareri, D. S., Bolger, N., & Tottenham, N. (2021). Longitudinal changes in amygdala, hippocampus, and cortisol development following early caregiving adversity. Developmental Cognitive Neuroscience, 48, 100916. https://doi.org/10.1016/j.dcn.2021.100916
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2020
Callaghan, B. L., Fields, A., Gee, D. G., Gabard-Durnam, L., Caldera, C., Humphreys, K. L., Goff, B., Flannery, J., Telzer, E. H., Shapiro, M., & Tottenham, N. (2020). Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, 32, 309-328. https://doi.org/10.1017/S0954579419000087
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Camacho, M. C., King, L. S., Ojha, A., Garcia, C. M., Sisk, L. M., Cichocki, A. C., Humphreys, K. L., & Gotlib, I. H. (2020). Cerebral blood flow in 5- to 8-month-olds: Regional tissue maturity is associated with infant affect. Developmental Science, 23, 5, e12928. https://doi.org/10.1111/desc.12928
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Cárdenas E. F., Kujawa, A., & Humphreys, K. L. (2020). Neurobiological changes during the peripartum period: Implications for health and behavior. Social Cognitive and Affective Neuroscience, 15, 1097-1110. https://doi.org/10.1093/scan/nsz091
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Castellanos, R., Spinel, M. Y., Phan, V., Orengo-Aguayo, R., Humphreys, K. L., & Flory, K. (2020). A systematic review and meta-analysis of cultural adaptations of mindfulness-based interventions for Hispanic populations. Mindfulness,11, 317-332. https://doi.org/10.1007/s12671-019-01210-x
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Gotlib, I. H., Goodman, S. H., & Humphreys, K. L. (2020). Studying the intergenerational transmission of risk for depression: Current status and future directions.C Current Directions in Psychological Science, 29, 174-179. https://doi.org/10.1177/0963721420901590
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Humphreys, K. L. (2020). Child maltreatment recurrence points to urgent need to improve systems for identification and prevention. Journal of the American Academy of Child and Adolescent Psychiatry, 59, 1102-1104. https://doi.org/10.1016/j.jaac.2020.07.005
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Humphreys, K. L., Camacho, M. C., Roth, M. C., & Estes, E. C. (2020). Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants. Developmental Cognitive Neuroscience, 46, 100877. https://doi.org/10.1016/j.dcn.2020.100877
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Humphreys, K. L., Guyon-Harris, K. L., Tibu, F., Wade, M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2020). Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16. Journal of Consulting and Clinical Psychology, 88, 1079-1090. https://dx.doi.org/10.1037/ccp0000613
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Humphreys, K. L., †LeMoult, J., Wear, J. G., Piersiak, H. A., Lee, A., & Gotlib, I. H. (2020). Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse & Neglect, 102, 104361. https://doi.org/10.1016/j.chiabu.2020.104361 **Selected as the 2020 Article of the Year in Child Abuse & Neglect**
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Humphreys, K. L., Machlin, L. S., Guyon-Harris, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2020). Psychosocial deprivation and receptive language: A two sample study. Journal of Neurodevelopmental Disorders, 12, 36. https://doi.org/10.1186/s11689-020-09341-2
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Humphreys, K. L., Myint, M. T., & Zeanah, C. H. (2020). Increased risk for family violence during the COVID-19 pandemic. Pediatrics, 146, e20200982. https://doi.org/10.1542/peds.2020-0982
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Humphreys, K. L., Sisk, L. M., Mancszak, E. M., Lin, J., & Gotlib, I. H. (2020). Depressive symptoms predict change in telomere length and mitochondrial DNA copy number across adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59, 1364-1370. https://doi.org/10.1016/j.jaac.2019.09.031
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Humphreys, K. L. & Salo, V. C. (2020). Expectable environments in early life. Current Opinion in Behavioral Sciences, 36, 115-119. https://doi.org/10.1016/j.cobeha.2020.09.004
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King, L. S., Dennis, E. L., Humphreys, K. L., Thompson, P. M., & Gotlib, I. H. (2020). Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls. Developmental Cognitive Neuroscience, 44, 100796. https://doi.org/10.1016/j.dcn.2020.100796
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LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J., Ip, E., & Gotlib, I. H. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59, 842-855. https://doi.org/10.1016/j.jaac.2019.10.011
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Miller, J. G., Ho, T. C., Humphreys, K. L., King, L. S., Foland-Ross, L. C., Colich, N. L., Ordaz, S. J., Lin, J., & Gotlib, I. H. (2020). Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation. Cerebral Cortex, 30, 4269-4280. https://doi.org/10.1093/cercor/bhaa057
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Moore, S. R., Humphreys, K. L., Colich, N. L., Davis, E. G., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., & Gotlib, I. H. (2020). Distinctions between sex and time in patterns of DNA methylation across puberty. BMC Genomics, 21, 389. https://doi.org/10.1186/s12864-020-06789-3
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Muscatell, K. A., Brosso, S. N., & Humphreys, K. L. (2020). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry, 25, 2189-2199. https://doi.org/10.1038/s41380-018-0259-2
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Robakis, T. K., Zhang, S., Rasgon, N. L., Li, T., Wang, T., Roth, M. C., Humphreys, K. L., Gotlib, I. H., Ho, M., Khechaduri, A., Watson, K., Roat-Shumway, S., Budhan, V. V., David, K. N., Crowe, S. D., Williams, K. E., & Urban, A. E. (2020). Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Translational Psychiatry, 10, 48. https://doi.org/10.1038/s41398-020-0703-3
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Salo, V. C., Schunck, S. J., & Humphreys, K. L. (2020). Depressive symptoms in parents are associated with reduced empathy toward their young children. PLoS ONE, 15, e0230636. https://doi.org/10.1371/journal.pone.0230636
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Zeanah, C. H. & Humphreys, K. L. (2020). Global prevalence of institutional care for children: A call for change. The Lancet Child & Adolescent Health, 4, 343-344. https://doi.org/10.1016/S2352-4642(20)30055-9
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2019
Callaghan, B. L., Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: An examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 664-671. https://doi.org/10.1016/j.bpsc.2019.02.001
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Dennis, E. L., Humphreys, K. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Irritability and brain volume in adolescents: Cross-sectional and longitudinal associations. Social Cognitive and Affective Neuroscience, 14, 687-698. https://doi.org/10.1093/scan/nsz053
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Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development, 21, 95-110. https://doi.org/10.1080/14616734.2018.1499208
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Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse & Neglect, 88, 96-106. https://doi.org/10.1016/j.chiabu.2018.11.005
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Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Gleason, M. M., Nelson, C. A., Fox, N. A., Zeanah, C. H. (2019). Disinhibited social engagement disorder in early childhood predicts reduced competence in early adolescence. Journal of Abnormal Child Psychology, 47, 1735-1745. https://doi.org/10.1007/s10802-019-00547-0
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Humphreys, K. L., †Moore, S. R., †Davis, E. G., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2019). DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: A prospective analysis. Translational Psychiatry, 9, 245. https://doi.org/10.1038/s41398-019-0582-7
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Humphreys, K. L. (2019). Early caregiving intervention holds promise for long-term improvements in neural function following adversity. Biological Psychiatry, 85, e15-e16. https://doi.org/10.1016/j.biopsych.2018.12.005
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Humphreys, K. L. (2019). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology, 48, 166-178. https://doi.org/10.1080/15374416.2018.1534209
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Humphreys, K. L. (2019). Understanding the link between early adversity and disease – Stress, immunity, and prevention. Brain, Behavior, and Immunity, 78, 1-2. https://doi.org/10.1016/j.bbi.2018.12.019
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Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (2019). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science, 22, e12775. https://doi.org/10.1111/desc.12775
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Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology, 47, 421-432. https://doi.org/10.1007/s10802-018-0443-5
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Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (2019). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, 31, 1477-1487. https://doi.org/10.1017/S0954579418001050
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Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2019). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology, 48, 781-789. https://doi.org/10.1080/15374416.2018.1460847
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King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2019). A person-centered approach to the assessment of early life stress: Associations with the volume of stress-sensitive brain regions in early adolescence. Development and Psychopathology, 31, 643-655. https://doi.org/10.1017/S0954579418000184
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King, L. S., Humphreys, K. L., & Gotlib, I. H. (2019). The neglect–enrichment continuum: Characterizing variation in early caregiving environments. Developmental Review, 51, 109-122. https://doi.org/10.1016/j.dr.2019.01.001
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Kircanski, K., Sisk, L. M., Ho, T. C., Humphreys, K. L., King, L. S., Colich, N. L., Ordaz, S. J., & Gotlib, I. H. (2019). Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. Development and Psychopathology, 31, 1011-1022. https://doi.org/10.1017/S0954579419000555
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LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2019). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology, 47, 199-207. https://doi.org/10.1007/s10802-018-0430-x
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2018
Ellwood-Lowe, M. E., Humphreys, K. L., Ordaz, S. J., Camacho, M. C., Sacchet, M. D., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. https://doi.org/10.1016/j.dcn.2017.12.005
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Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 329-335. https://doi.org/10.1016/j.jaac.2018.02.009
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Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. https://doi.org/10.1016/j.jad.2018.05.072
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Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59, 811-821. https://doi.org/10.1111/jcpp.12865
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Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24, 261-276. https://doi.org/10.1080/09297049.2016.1264578
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Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. https://doi.org/10.1016/j.chiabu.2018.03.016
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Zeanah, C. H. & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 637-644. https://doi.org/10.1016/j.jaac.2018.06.007
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2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29, 1851-1864. https://doi.org/10.1017/S0954579417001444
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Davis, E. G., †Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2017). Accelerated DNA methylation age in adolescent girls: Associations with elevated diurnal cortisol and reduced hippocampal volume. Translational Psychiatry, 7, e1223. https://doi.org/10.1038/tp.2017.188
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Flannery, J. E., Gabard-Durnam, L. J., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E. H., Humphreys, K. L., Lumian, D. S., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166. https://doi.org/10.1016/j.dcn.2017.03.006
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Galán, C. A. & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times, 34, 1-3.
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Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience, 12, 1460-1469. https://doi.org/10.1093/scan/nsx065
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Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29, 675-684. https://doi.org/10.1017/S0954579417000256
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Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms.
Journal of Clinical Child and Adolescent Psychology, 46, 903-914. https://doi.org/10.1080/15374416.2015.1094739
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King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A. N., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroenddocrinology, 77, 68-74. https://doi.org/10.1016/j.psyneuen.2016.11.024
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VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017). Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and Psychopathology, 29, 519-533. https://doi.org/10.1017/S0954579417000153
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Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children: Insights from the Bucharest Early Intervention Project.
Current Opinion in Psychology, 15, 182-188. https://doi.org/10.1016/j.copsyc.2017.02.024
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2016
Gabard-Durnam, L. J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K. L., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36, 4771-4784. https://doi.org/10.1523/JNEUROSCI.0598-16.2016
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Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37, 476-485. https://doi.org/10.1002/imhj.21592
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Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L., Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57, 1135-1144. https://doi.org/10.1111/jcpp.12578
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Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. https://doi.org/10.1016/j.psychres.2016.09.023
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Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44, 1023-1032. https://doi.org/10.1007/s10802-015-0095-7
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Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57, 1174-1182. https://doi.org/10.1111/jcpp.12607
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Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16, 101-109. https://doi.org/10.1037/emo0000116
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Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161, 84-93. https://doi.org/10.1002/ajpa.23010
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Silvers, J. A., Lumian, D. S., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D. S., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala–hippocampal PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36, 6420-6430. https://doi.org/10.1523/JNEUROSCI.0038-16.2016
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Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. Journal of Attention Disorders, 20, 695-703. https://doi.org/10.1177/1087054712465337
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2015
Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis. Clinical Child and Family Psychology Review, 18, 50-76. https://doi.org/10.1007/s10567-014-0177-z
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Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27, 347-367. https://doi.org/10.1007/s10567-014-0177-z
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Brett, Z. H., †Humphreys, K. L., Smyke, A. T., Gleason, M., Nelson, C. A., Zeanah, C. H., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter linked polymorphic region (5-HTTLPR) genotype moderates the longitudinal impact of early caregiving on externalizing behavior. Development and Psychopathology, 27, 7-18. https://doi.org/10.1017/S0954579414001266
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Brett, Z. H., Sheridan, M., Humphreys, K. L., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2015). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39, 150-160. https://doi.org/10.1177/0165025414538557
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Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter genotype (5HTTLPR) moderates the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36, 409-416. https://doi.org/10.1097/DBP.0000000000000171
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Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: Follow-up of an open, randomized controlled trial. The Lancet Psychiatry, 2, 625-634. https://doi.org/10.1016/S2215-0366(15)00095-4
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Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration-exploitation strategy is dependent on early experience. Developmental Psychobiology, 57, 313-321. https://doi.org/10.1002/dev.21293
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Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 977-983. https://doi.org/10.1016/j.jaac.2015.09.010 **Received the Norbert and Charlotte Rieger Award for Scientific Achievement from the American Academy of Child and Adolescent Psychiatry (Journal of the American Academy of Child and Adolescent Psychiatry outstanding paper of the year)**
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Humphreys, K. L. & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40, 154-170. https://doi.org/10.1038/npp.2014.165
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Telzer, E. H., Flannery, J., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. G., & Tottenham, N. (2015). "The cooties effect": Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 27, 1685-1696. https://doi.org/10.1162/jocn_a_00813
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2014
Gabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 years: A cross-sectional study. NeuroImage, 95, 193-207. https://doi.org/10.1016/j.neuroimage.2014.03.038
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Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala-prefrontal circuitry during childhood but not during adolescence. Psychological Science, 25, 2067-2078. https://doi.org/10.1177/0956797614550878
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Gee, D. G., Gabard-Durnam, L. J., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E. H., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110, 15638-15643. https://doi.org/10.1073/pnas.1307893110
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Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of Catechol-O-methyltransferase genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24, , 454-457. https://doi.org/10.1089/cap.2014.0077
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Lee, S. S. & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children. Experimental and Clinical Psychopharmacology, 22, 100-109. https://doi.org/10.1037/a0035338
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Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19, 145-155. https://doi.org/10.1177/1077559514543827
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Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing.
Infant Mental Health Journal, 35, 123-131. https://doi.org/10.1002/imhj.21428
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2013
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33, 4584-4593. https://doi.org/10.1523/JNEUROSCI.3446-12.2013
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Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. https://doi.org/10.1016/j.neuroscience.2012.12.010
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Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70, 740-749. https://doi.org/10.1001/jamapsychiatry.2013.1273
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Humphreys, K. L., Katz, S. J., Lee, S. S., Hammen, C., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent–child difficulties in two complementary samples. Journal of Abnormal Psychology, 122, 854-867. https://doi.org/10.1037/a0033895
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Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54, 709-715. https://doi.org/10.1016/j.paid.2012.11.031
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Olsavsky, A. K., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74, 853-860. https://doi.org/10.1016/j.biopsych.2013.05.025
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Telzer, E. H., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33, 13484-13488. https://doi.org/10.1523/JNEUROSCI.1272-13.2013
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Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race is not present in childhood but emerges over adolescence. Journal of Cognitive Neuroscience, 25, 234-244. https://doi.org/10.1162/jocn_a_00311
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2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41, 370-377. https://doi.org/10.1080/15374416.2012.656557
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Humphreys, K. L., Foley, K. M., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151. https://doi.org/10.1037/a0022644
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Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorder, 16, 267-275. https://doi.org/10.1177/1087054710387264
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Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. G., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among Vietnam combat veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25, 416-425. https://doi.org/10.1002/jts.21729
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Tottenham, N., Shapiro, M., Telzer, E. H., & Humphreys, K. L. (2012). Amygdala response to mother. Developmental Science, 15, 307-319. https://doi.org/10.1111/j.1467-7687.2011.01128.x
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2011
Castel, A. D., Humphreys, K. L., Lee, S. S., Galván, A., Balota, D. A., & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47, 1553-1564. https://doi.org/10.1037/a0025623
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Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25, 15-24. https://doi.org/10.1037/a0020298
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Feinstein, B. A., Humphreys, K. L., Bovin, M. J., Marx, B. P., & Resick, P. A. (2011). Victim-offender relationship status moderates the relationships of peritraumatic emotional responses, active resistance, and posttraumatic stress symptomatology in female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3, 192-200. https://doi.org/10.1037/a0021652
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Humphreys, K. L. & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. https://doi.org/10.1007/s10862-011-9237-6
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Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31, 328-341. https://doi.org/10.1016/j.cpr.2011.01.006
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2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relationship to posttraumatic stress symptomatology. Journal of Interpersonal Violence, 25, 358-373. https://doi.org/10.1177/0886260509334412
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Heflinger, C. A. & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of one state’s public service system. Psychological Services, 5, 139-152. https://doi.org/10.1037/1541-1559.5.2.139
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Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Grove, W. M., Kaloupek, D. G., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196, 605-611. https://doi.org/10.1097/NMD.0b013e318181326d
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