Electronic copies of these publications are available for individual, non-commercial use only (†equal contribution)
2020 and in press
Colich, N. L., Sheridan, M. A., Humphreys, K. L., Wade, M., Tibu, F., Nelson, C. A., Zeanah, C. H., Fox, N. A., & McLaughlin, K. A. (in press). Heightened sensitivity to the caregiving environment during adolescence: Implications for recovery following early-life adversity. Journal of Child Psychology and Psychiatry.
Humphreys, K. L. & Salo, V. C. (in press). Expectable environments in early life. Current Opinion in Behavioral Sciences.
Humphreys, K. L., Guyon-Harris, K. L., Tibu, F., Wade, M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16. Journal of Consulting and Clinical Psychology.
Guyon-Harris, K. L., Humphreys, K. L., & Zeanah, C. H. (in press). Adverse caregiving in early life: The trauma and deprivation distinction in young children. Journal of Infant Mental Health.
Humphreys, K. L., Machlin, L. S., Guyon-Harris, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychosocial deprivation and receptive language: A two sample study. Journal of Neurodevelopmental Disorders.
Humphreys, K. L. (in press). Child maltreatment recurrence points to urgent need to improve systems for identification and prevention. Journal of the American Academy of Child and Adolescent Psychiatry. doi:10.1016/j.jaac.2020.07.005
Humphreys, K. L., Sisk, L. M., Mancszak, E. M., Lin, J., & Gotlib, I. H. (in press). Depressive symptoms predict change in telomere length and mitochondrial DNA copy number across adolescence. Journal of the American Academy of Child and Adolescent Psychiatry. http://doi.org/10.1016/j.jaac.2019.09.031
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Tibu, F., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2020). Early caregiving quality predicts consistency of competent functioning from middle childhood to adolescence following early psychosocial deprivation. Development and Psychopathology. https://doi.org/10.1017/S0954579419001500
King, L. S., Dennis, E. L., Humphreys, K. L., Thompson, P. M., & Gotlib, I. H. (2020). Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls. Developmental Cognitive Neuroscience, 44. http://doi.org/10.1016/j.dcn.2020.100796
Callaghan, B. L., Fields, A., Gee, D. G., Gabard-Durnam, L., Caldera, C., Humphreys, K. L., Goff, B., Flannery, J., Telzer, E. H., Shapiro, M., & Tottenham, N. (2020). Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, 32(1), 309-328. http://doi.org/10.1017/S0954579419000087
Castellanos, R., Spinel, M. Y., Phan, V., Orengo-Aguayo, R., Humphreys, K. L., & Flory, K. (2020). A systematic review and meta-analysis of cultural adaptations of mindfulness-based interventions for Hispanic populations. Mindfulness, 11, 317-332. http://doi.org/10.1007/s12671-019-01210-x
Gotlib, I. H., Goodman, S. H., & Humphreys, K. L. (2020). Studying the intergenerational transmission of risk for depression: Current status and future directions. Current Directions in Psychological Science, 29(2), 174-179. http://doi.org/10.1177/0963721420901590
Humphreys, K. L., Myint, M. T., & Zeanah, C. H. (2020). Increased risk for family violence during the COVID-19 pandemic. Pediatrics, 146(1), e20200982. http://doi.org/10.1542/peds.2020-0982
Humphreys, K. L., LeMoult, J., Wear, J. G., Piersiak, H. A., Lee, A., & Gotlib, I. H. (2020). Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse & Neglect, 102. http://doi.org/10.1016/j.chiabu.2020.104361
LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J., Ip, E., & Gotlib, I. H. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59(7), 842-855. http://doi.org/10.1016/j.jaac.2019.10.011
Miller, J. G., Ho, T. C., Humphreys, K. L., King, L. S., Foland-Ross, L. C., Colich, N. L., Ordaz, S. J., Lin, J., & Gotlib, I. H. (2020). Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation. Cerebral Cortex, 30(7), 4269-4280. http://doi.org/10.1093/cercor/bhaa057
Moore, S. R., Humphreys, K. L., Colich, N. L., Davis, E. G., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., & Gotlib, I. H. (2020). Distinctions between sex and time in patterns of DNA methylation across puberty. BMC Genomics, 21(1), 389. http://doi.org/10.1186/s12864-020-06789-3
Muscatell, K. A., Brosso, S. N., & Humphreys, K. L. (2020). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry, 25, 2189-2199. http://doi.org/10.1038/s41380-018-0259-2
Robakis, T. K., Zhang, S., Rasgon, N. L., Li, T., Wang, T., Roth, M. C., Humphreys, K. L., Gotlib, I. H., Ho, M., Khechaduri, A., Watson, K., Roat-Shumway, S., Budhan, V. V., David, K. N., Crowe, S. D., Williams, K. E., & Urban, A. E. (2020). Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Translational Psychiatry, 10(1), 48. http://doi.org/10.1038/s41398-020-0703-3
Salo, V. C., Schunck, S. J., & Humphreys, K. L. (2020). Depressive symptoms in parents are associated with reduced empathy toward their young children. PLoS ONE, 15(3), e0230636. http://doi.org/10.1371/journal.pone.0230636
Zeanah, C. H. & Humphreys, K. L. (2020). Global prevalence of institutional care for children: A call for change. The Lancet Child & Adolescent Health, 4(5), 343-344. http://doi.org/10.1016/S2352-4642(20)30055-9
2019
Callaghan, B. L., Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: An examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(7), 664-671. http://doi.org/10.1016/j.bpsc.2019.02.001
Camacho, M. C., King, L. S., Ojha, A., Garcia, C. M., Sisk, L. M., Cichocki, A. C., Humphreys, K. L., & Gotlib, I. H. (2019). Cerebral blood flow in 5- to 8-month-olds: Regional tissue maturity is associated with infant affect. Developmental Science, e12928. http://doi.org/10.1111/desc.12928
Cárdenas E. F., Kujawa, A., & Humphreys, K. L. (2019). Neurobiological changes during the peripartum period: Implications for health and behavior. Social Cognitive and Affective Neuroscience, 1-14. http://doi.org/10.1093/scan/nsz091
Dennis, E. L., Humphreys, K. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Irritability and brain volume in adolescents: Cross-sectional and longitudinal associations. Social Cognitive and Affective Neuroscience, 14(7), 687-698. http://doi.org/10.1093/scan/nsz053
Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development, 21(2), 95-110. http://doi.org/10.1080/14616734.2018.1499208
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse and Neglect, 88, 96-106. http://doi.org/10.1016/j.chiabu.2018.11.005
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Gleason, M. M., Nelson, C. A., Fox, N. A., Zeanah, C. H. (2019). Disinhibited social engagement disorder in early childhood predicts reduced competence in early adolescence. Journal of Abnormal Child Psychology, 47(10), 1735-1745. http://doi.org/10.1007/s10802-019-00547-0
Humphreys, K. L., Moore, S. R., Davis, E. G., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2019). DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: A prospective analysis. Translational Psychiatry, 9(1), 245. http://doi.org/10.1038/s41398-019-0582-7
Humphreys, K. L. (2019). Early caregiving intervention holds promise for long-term improvements in neural function following adversity. Biological Psychiatry, 85(4), e15-e16. http://doi.org/10.1016/j.biopsych.2018.12.005
Humphreys, K. L. (2019). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology, 48(1), 166-178. http://doi.org/10.1080/15374416.2018.1534209
Humphreys, K. L. (2019). Understanding the link between early adversity and disease – stress, immunity, and prevention. Brain, Behavior, and Immunity, 78, 1-2. http://doi.org/10.1016/j.bbi.2018.12.019
Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (2019). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science, 22(3), e12775. http://doi.org/10.1111/desc.12775
Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology, 47(3), 421-432. http://doi.org/10.1007/s10802-018-0443-5
Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (2019). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, 31(4), 1477-1487. http://doi.org/10.1017/S0954579418001050
Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2019). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology, 48(5), 781-789. http://doi.org/10.1080/15374416.2018.1460847
King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2019). A person-centered approach to the assessment of early life stress: Associations with the volume of stress-sensitive brain regions in early adolescence. Development and Psychopathology, 31(2), 643-655. http://doi.org/10.1017/S0954579418000184
King, L. S., Humphreys, K. L., & Gotlib, I. H. (2019). The neglect–enrichment continuum: Characterizing variation in early caregiving environments. Developmental Review, 51, 109-122. http://doi.org/10.1016/j.dr.2019.01.001
Kircanski, K., Sisk, L. M., Ho, T. C., Humphreys, K. L., King, L. S., Colich, N. L., Ordaz, S. J., & Gotlib, I. H. (2019). Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. Development and Psychopathology, 31(3), 1011-1022. http://doi.org/10.1017/S0954579419000555
LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2019). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology, 47(2), 199-207. http://doi.org/10.1007/s10802-018-0430-x
2018
Ellwood-Lowe, M. E., Humphreys, K. L., Ordaz, S. J., Camacho, M. C., Sacchet, M. D., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume
trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. http://doi.org/10.1016/j.dcn.2017.12.005
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57(5), 329-335. http://doi.org/10.1016/j.jaac.2018.02.009
Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. http://doi.org/10.1016/j.jad.2018.05.072
Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59(7), 811-821. http://doi.org/10.1111/jcpp.12865
Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24(2), 261-276. http://doi.org/10.1080/09297049.2016.1264578
Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. http://doi.org/10.1016/j.chiabu.2018.03.016
Zeanah, C. H. & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57(9), 637-644. http://doi.org/10.1016/j.jaac.2018.06.007
2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29(5), 1851-1864. http://doi.org/10.1017/S0954579417001444
Davis, E. G., Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2017). Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume. Translational Psychiatry, 7(8), e1223. http://doi.org/10.1038/tp.2017.188
Flannery, J. E., Gabard-Durnam, L. J., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E. H., Humphreys, K. L., Lumian, D. S., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166. http://doi.org/10.1016/j.dcn.2017.03.006
Galán, C. A. & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times, 34, 1-3.
Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience, 12(9), 1460-1469. http://doi.org/10.1093/scan/nsx065
Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29(2), 675-684. http://doi.org/10.1017/S0954579417000256
Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms. Journal of Clinical Child and Adolescent Psychology, 46(6), 903-914. http://doi.org/10.1080/15374416.2015.1094739
King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A. N., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroendocrinology, 77, 68-74. http://doi.org/10.1016/j.psyneuen.2016.11.024
VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017).
Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and Psychopathology, 29(2), 519-533. http://doi.org/10.1017/S0954579417000153
Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children: Insights from the Bucharest Early Intervention Project. Current Opinion in Psychology, 15, 182-188. http://doi.org/10.1016/j.copsyc.2017.02.024
2016
Gabard-Durnam, L. J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K. L., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36(17), 4771-4784. http://doi.org/10.1523/JNEUROSCI.0598-16.2016
Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37(5), 476-485. http://doi.org/10.1002/imhj.21592
Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L., Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57(10), 1135-1144. http://doi.org/10.1111/jcpp.12578
Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. http://doi.org/10.1016/j.psychres.2016.09.023
Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44(5), 1023-1032. http://doi.org/10.1007/s10802-015-0095-7
Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57(10), 1174-1182. http://doi.org/10.1111/jcpp.12607
Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16(1), 101-109. http://doi.org/10.1037/emo0000116
Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161(1), 84-93. http://doi.org/10.1002/ajpa.23010
Silvers, J. A., Lumian, D. S., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D. S., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala-hippocampal-PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36(24), 6420-6430. http://doi.org/10.1523/JNEUROSCI.0038-16.2016
Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. Journal of Attention Disorders, 20(8), 695-703. http://doi.org/10.1177/1087054712465337
2015
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Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis. Clinical Child and Family Psychology Review, 18(1), 50-76. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27(2), 347-367. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Sheridan, M., Humphreys, K., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2015). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39(2), 150-160. http://doi.org/10.1177/0165025414538557
Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter genotype (5HTTLPR) moderates
the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36(6), 409-416. http://doi.org/10.1017/S0954579414001266
Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: Follow-up of an open, randomised controlled trial. The Lancet Psychiatry, 2(7), 625-634. http://doi.org/10.1016/S2215-0366(15)00095-4
Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration-exploitation strategy is dependent on early experience. Developmental Psychobiology, 57(3), 313-321. http://doi.org/10.1002/dev.21293
Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54(12), 977-983. http://doi.org/10.1016/j.jaac.2015.09.010
Humphreys, K. L. & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40(1), 154-170. http://doi.org/10.1038/npp.2014.165
Telzer, E. H., Flannery, J., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. G., & Tottenham, N. (2015). "The cooties effect": Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 27(9), 1685-1696. http://doi.org/10.1162/jocn_a_00813
2014
Gabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 years: A cross-sectional study. NeuroImage, 95, 193-207. http://doi.org/10.1016/j.neuroimage.2014.03.038
Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala-prefrontal circuitry during childhood but not during adolescence. Psychological Science, 25(11), 2067-2078. http://doi.org/10.1177/0956797614550878
Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of Catechol-O-methyltransferase genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24(8), 454-457. http://doi.org/10.1089/cap.2014.0077
Lee, S. S. & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children. Experimental and Clinical Psychopharmacology, 22(2), 100-109. http://doi.org/10.1037/a0035338
Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19(3-4), 145-155. http://doi.org/10.1177/1077559514543827
Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Mental Health Journal, 35(2), 123-131. http://doi.org/10.1002/imhj.21428
2013
Gee, D. G., Gabard-Durnam, L. J., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E. H., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110(39), 15638-15643. http://doi.org/10.1073/pnas.1307893110
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33(10), 4584-4593. http://doi.org/10.1523/JNEUROSCI.3446-12.2013
Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. http://doi.org/10.1016/j.neuroscience.2012.12.010
Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70(7), 740-749. http://doi.org/10.1001/jamapsychiatry.2013.1273
Humphreys, K. L., Katz, S. J., Lee, S. S., Hammen, C., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent-child difficulties in two complementary samples. Journal of Abnormal Psychology, 122(3), 854-867. http://doi.org/10.1037/a0033895
Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54(6), 709-715. http://doi.org/10.1016/j.paid.2012.11.031
Olsavsky, A. K., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74(11), 853-860. http://doi.org/10.1016/j.biopsych.2013.05.025
Telzer, E. H., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33(33), 13484-13488. http://doi.org/10.1523/JNEUROSCI.1272-13.2013
Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race is not present in childhood but emerges over adolescence. Journal of Cognitive Neuroscience, 25(2), 234-244. http://doi.org/10.1162/jocn_a_00311
2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41(3), 370-377. http://doi.org/10.1080/15374416.2012.656557
Humphreys, K. L., Foley, K. M., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151. http://doi.org/10.1037/a0022644
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16(4), 267-275. http://doi.org/10.1177/1087054710387264
Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. G., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among Vietnam combat veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25(4), 416-425. http://doi.org/10.1002/jts.21729
Tottenham, N., Shapiro, M., Telzer, E. H., & Humphreys, K. L. (2012). Amygdala response to mother. Developmental Science, 15(3), 307-319. http://doi.org/10.1111/j.1467-7687.2011.01128.x
2011
Castel, A. D., Humphreys, K. L., Lee, S. S., Galván, A., Balota, D. A., & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47(6), 1553-1564. http://doi.org/10.1037/a0025623
Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25(1), 15-24. http://doi.org/10.1037/a0020298
Feinstein, B. A., Humphreys, K. L., Bovin, M. J., Marx, B. P., & Resick, P. A. (2011). Victim-offender relationship status moderates the relationships of peritraumatic emotional responses, active resistance, and posttraumatic stress symptomatology in female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3(2), 192-200. http://doi.org/10.1037/a0021652
Humphreys, K. L. & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. http://doi.org/10.1007/s10862-011-9237-6
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31(3), 328-341. http://doi.org/10.1016/j.cpr.2011.01.006
2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relationship to posttraumatic stress symptomatology. Journal of Interpersonal Violence, 25(2), 358-373. http://doi.org/10.1177/0886260509334412
Heflinger, C. A. & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of one state’s public service system. Psychological Services, 5, 139-152. http://doi.org/10.1037/1541-1559.5.2.139
Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Grove, W. M., Kaloupek, D. G., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196(8), 605-611. http://doi.org/10.1097/NMD.0b013e318181326d
2020 and in press
Colich, N. L., Sheridan, M. A., Humphreys, K. L., Wade, M., Tibu, F., Nelson, C. A., Zeanah, C. H., Fox, N. A., & McLaughlin, K. A. (in press). Heightened sensitivity to the caregiving environment during adolescence: Implications for recovery following early-life adversity. Journal of Child Psychology and Psychiatry.
Humphreys, K. L. & Salo, V. C. (in press). Expectable environments in early life. Current Opinion in Behavioral Sciences.
Humphreys, K. L., Guyon-Harris, K. L., Tibu, F., Wade, M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16. Journal of Consulting and Clinical Psychology.
Guyon-Harris, K. L., Humphreys, K. L., & Zeanah, C. H. (in press). Adverse caregiving in early life: The trauma and deprivation distinction in young children. Journal of Infant Mental Health.
Humphreys, K. L., Machlin, L. S., Guyon-Harris, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychosocial deprivation and receptive language: A two sample study. Journal of Neurodevelopmental Disorders.
Humphreys, K. L. (in press). Child maltreatment recurrence points to urgent need to improve systems for identification and prevention. Journal of the American Academy of Child and Adolescent Psychiatry. doi:10.1016/j.jaac.2020.07.005
Humphreys, K. L., Sisk, L. M., Mancszak, E. M., Lin, J., & Gotlib, I. H. (in press). Depressive symptoms predict change in telomere length and mitochondrial DNA copy number across adolescence. Journal of the American Academy of Child and Adolescent Psychiatry. http://doi.org/10.1016/j.jaac.2019.09.031
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Tibu, F., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2020). Early caregiving quality predicts consistency of competent functioning from middle childhood to adolescence following early psychosocial deprivation. Development and Psychopathology. https://doi.org/10.1017/S0954579419001500
King, L. S., Dennis, E. L., Humphreys, K. L., Thompson, P. M., & Gotlib, I. H. (2020). Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls. Developmental Cognitive Neuroscience, 44. http://doi.org/10.1016/j.dcn.2020.100796
Callaghan, B. L., Fields, A., Gee, D. G., Gabard-Durnam, L., Caldera, C., Humphreys, K. L., Goff, B., Flannery, J., Telzer, E. H., Shapiro, M., & Tottenham, N. (2020). Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, 32(1), 309-328. http://doi.org/10.1017/S0954579419000087
Castellanos, R., Spinel, M. Y., Phan, V., Orengo-Aguayo, R., Humphreys, K. L., & Flory, K. (2020). A systematic review and meta-analysis of cultural adaptations of mindfulness-based interventions for Hispanic populations. Mindfulness, 11, 317-332. http://doi.org/10.1007/s12671-019-01210-x
Gotlib, I. H., Goodman, S. H., & Humphreys, K. L. (2020). Studying the intergenerational transmission of risk for depression: Current status and future directions. Current Directions in Psychological Science, 29(2), 174-179. http://doi.org/10.1177/0963721420901590
Humphreys, K. L., Myint, M. T., & Zeanah, C. H. (2020). Increased risk for family violence during the COVID-19 pandemic. Pediatrics, 146(1), e20200982. http://doi.org/10.1542/peds.2020-0982
Humphreys, K. L., LeMoult, J., Wear, J. G., Piersiak, H. A., Lee, A., & Gotlib, I. H. (2020). Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse & Neglect, 102. http://doi.org/10.1016/j.chiabu.2020.104361
LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J., Ip, E., & Gotlib, I. H. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59(7), 842-855. http://doi.org/10.1016/j.jaac.2019.10.011
Miller, J. G., Ho, T. C., Humphreys, K. L., King, L. S., Foland-Ross, L. C., Colich, N. L., Ordaz, S. J., Lin, J., & Gotlib, I. H. (2020). Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation. Cerebral Cortex, 30(7), 4269-4280. http://doi.org/10.1093/cercor/bhaa057
Moore, S. R., Humphreys, K. L., Colich, N. L., Davis, E. G., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., & Gotlib, I. H. (2020). Distinctions between sex and time in patterns of DNA methylation across puberty. BMC Genomics, 21(1), 389. http://doi.org/10.1186/s12864-020-06789-3
Muscatell, K. A., Brosso, S. N., & Humphreys, K. L. (2020). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry, 25, 2189-2199. http://doi.org/10.1038/s41380-018-0259-2
Robakis, T. K., Zhang, S., Rasgon, N. L., Li, T., Wang, T., Roth, M. C., Humphreys, K. L., Gotlib, I. H., Ho, M., Khechaduri, A., Watson, K., Roat-Shumway, S., Budhan, V. V., David, K. N., Crowe, S. D., Williams, K. E., & Urban, A. E. (2020). Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Translational Psychiatry, 10(1), 48. http://doi.org/10.1038/s41398-020-0703-3
Salo, V. C., Schunck, S. J., & Humphreys, K. L. (2020). Depressive symptoms in parents are associated with reduced empathy toward their young children. PLoS ONE, 15(3), e0230636. http://doi.org/10.1371/journal.pone.0230636
Zeanah, C. H. & Humphreys, K. L. (2020). Global prevalence of institutional care for children: A call for change. The Lancet Child & Adolescent Health, 4(5), 343-344. http://doi.org/10.1016/S2352-4642(20)30055-9
2019
Callaghan, B. L., Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: An examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(7), 664-671. http://doi.org/10.1016/j.bpsc.2019.02.001
Camacho, M. C., King, L. S., Ojha, A., Garcia, C. M., Sisk, L. M., Cichocki, A. C., Humphreys, K. L., & Gotlib, I. H. (2019). Cerebral blood flow in 5- to 8-month-olds: Regional tissue maturity is associated with infant affect. Developmental Science, e12928. http://doi.org/10.1111/desc.12928
Cárdenas E. F., Kujawa, A., & Humphreys, K. L. (2019). Neurobiological changes during the peripartum period: Implications for health and behavior. Social Cognitive and Affective Neuroscience, 1-14. http://doi.org/10.1093/scan/nsz091
Dennis, E. L., Humphreys, K. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Irritability and brain volume in adolescents: Cross-sectional and longitudinal associations. Social Cognitive and Affective Neuroscience, 14(7), 687-698. http://doi.org/10.1093/scan/nsz053
Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development, 21(2), 95-110. http://doi.org/10.1080/14616734.2018.1499208
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse and Neglect, 88, 96-106. http://doi.org/10.1016/j.chiabu.2018.11.005
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Gleason, M. M., Nelson, C. A., Fox, N. A., Zeanah, C. H. (2019). Disinhibited social engagement disorder in early childhood predicts reduced competence in early adolescence. Journal of Abnormal Child Psychology, 47(10), 1735-1745. http://doi.org/10.1007/s10802-019-00547-0
Humphreys, K. L., Moore, S. R., Davis, E. G., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2019). DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: A prospective analysis. Translational Psychiatry, 9(1), 245. http://doi.org/10.1038/s41398-019-0582-7
Humphreys, K. L. (2019). Early caregiving intervention holds promise for long-term improvements in neural function following adversity. Biological Psychiatry, 85(4), e15-e16. http://doi.org/10.1016/j.biopsych.2018.12.005
Humphreys, K. L. (2019). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology, 48(1), 166-178. http://doi.org/10.1080/15374416.2018.1534209
Humphreys, K. L. (2019). Understanding the link between early adversity and disease – stress, immunity, and prevention. Brain, Behavior, and Immunity, 78, 1-2. http://doi.org/10.1016/j.bbi.2018.12.019
Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (2019). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science, 22(3), e12775. http://doi.org/10.1111/desc.12775
Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology, 47(3), 421-432. http://doi.org/10.1007/s10802-018-0443-5
Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (2019). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, 31(4), 1477-1487. http://doi.org/10.1017/S0954579418001050
Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2019). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology, 48(5), 781-789. http://doi.org/10.1080/15374416.2018.1460847
King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2019). A person-centered approach to the assessment of early life stress: Associations with the volume of stress-sensitive brain regions in early adolescence. Development and Psychopathology, 31(2), 643-655. http://doi.org/10.1017/S0954579418000184
King, L. S., Humphreys, K. L., & Gotlib, I. H. (2019). The neglect–enrichment continuum: Characterizing variation in early caregiving environments. Developmental Review, 51, 109-122. http://doi.org/10.1016/j.dr.2019.01.001
Kircanski, K., Sisk, L. M., Ho, T. C., Humphreys, K. L., King, L. S., Colich, N. L., Ordaz, S. J., & Gotlib, I. H. (2019). Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. Development and Psychopathology, 31(3), 1011-1022. http://doi.org/10.1017/S0954579419000555
LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2019). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology, 47(2), 199-207. http://doi.org/10.1007/s10802-018-0430-x
2018
Ellwood-Lowe, M. E., Humphreys, K. L., Ordaz, S. J., Camacho, M. C., Sacchet, M. D., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume
trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. http://doi.org/10.1016/j.dcn.2017.12.005
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57(5), 329-335. http://doi.org/10.1016/j.jaac.2018.02.009
Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. http://doi.org/10.1016/j.jad.2018.05.072
Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59(7), 811-821. http://doi.org/10.1111/jcpp.12865
Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24(2), 261-276. http://doi.org/10.1080/09297049.2016.1264578
Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. http://doi.org/10.1016/j.chiabu.2018.03.016
Zeanah, C. H. & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57(9), 637-644. http://doi.org/10.1016/j.jaac.2018.06.007
2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29(5), 1851-1864. http://doi.org/10.1017/S0954579417001444
Davis, E. G., Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2017). Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume. Translational Psychiatry, 7(8), e1223. http://doi.org/10.1038/tp.2017.188
Flannery, J. E., Gabard-Durnam, L. J., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E. H., Humphreys, K. L., Lumian, D. S., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166. http://doi.org/10.1016/j.dcn.2017.03.006
Galán, C. A. & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times, 34, 1-3.
Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience, 12(9), 1460-1469. http://doi.org/10.1093/scan/nsx065
Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29(2), 675-684. http://doi.org/10.1017/S0954579417000256
Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms. Journal of Clinical Child and Adolescent Psychology, 46(6), 903-914. http://doi.org/10.1080/15374416.2015.1094739
King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A. N., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroendocrinology, 77, 68-74. http://doi.org/10.1016/j.psyneuen.2016.11.024
VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017).
Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and Psychopathology, 29(2), 519-533. http://doi.org/10.1017/S0954579417000153
Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children: Insights from the Bucharest Early Intervention Project. Current Opinion in Psychology, 15, 182-188. http://doi.org/10.1016/j.copsyc.2017.02.024
2016
Gabard-Durnam, L. J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K. L., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36(17), 4771-4784. http://doi.org/10.1523/JNEUROSCI.0598-16.2016
Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37(5), 476-485. http://doi.org/10.1002/imhj.21592
Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L., Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57(10), 1135-1144. http://doi.org/10.1111/jcpp.12578
Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. http://doi.org/10.1016/j.psychres.2016.09.023
Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44(5), 1023-1032. http://doi.org/10.1007/s10802-015-0095-7
Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57(10), 1174-1182. http://doi.org/10.1111/jcpp.12607
Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16(1), 101-109. http://doi.org/10.1037/emo0000116
Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161(1), 84-93. http://doi.org/10.1002/ajpa.23010
Silvers, J. A., Lumian, D. S., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D. S., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala-hippocampal-PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36(24), 6420-6430. http://doi.org/10.1523/JNEUROSCI.0038-16.2016
Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. Journal of Attention Disorders, 20(8), 695-703. http://doi.org/10.1177/1087054712465337
2015
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Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis. Clinical Child and Family Psychology Review, 18(1), 50-76. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27(2), 347-367. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Sheridan, M., Humphreys, K., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2015). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39(2), 150-160. http://doi.org/10.1177/0165025414538557
Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter genotype (5HTTLPR) moderates
the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36(6), 409-416. http://doi.org/10.1017/S0954579414001266
Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: Follow-up of an open, randomised controlled trial. The Lancet Psychiatry, 2(7), 625-634. http://doi.org/10.1016/S2215-0366(15)00095-4
Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration-exploitation strategy is dependent on early experience. Developmental Psychobiology, 57(3), 313-321. http://doi.org/10.1002/dev.21293
Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54(12), 977-983. http://doi.org/10.1016/j.jaac.2015.09.010
Humphreys, K. L. & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40(1), 154-170. http://doi.org/10.1038/npp.2014.165
Telzer, E. H., Flannery, J., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. G., & Tottenham, N. (2015). "The cooties effect": Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 27(9), 1685-1696. http://doi.org/10.1162/jocn_a_00813
2014
Gabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 years: A cross-sectional study. NeuroImage, 95, 193-207. http://doi.org/10.1016/j.neuroimage.2014.03.038
Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala-prefrontal circuitry during childhood but not during adolescence. Psychological Science, 25(11), 2067-2078. http://doi.org/10.1177/0956797614550878
Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of Catechol-O-methyltransferase genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24(8), 454-457. http://doi.org/10.1089/cap.2014.0077
Lee, S. S. & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children. Experimental and Clinical Psychopharmacology, 22(2), 100-109. http://doi.org/10.1037/a0035338
Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19(3-4), 145-155. http://doi.org/10.1177/1077559514543827
Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Mental Health Journal, 35(2), 123-131. http://doi.org/10.1002/imhj.21428
2013
Gee, D. G., Gabard-Durnam, L. J., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E. H., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110(39), 15638-15643. http://doi.org/10.1073/pnas.1307893110
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33(10), 4584-4593. http://doi.org/10.1523/JNEUROSCI.3446-12.2013
Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. http://doi.org/10.1016/j.neuroscience.2012.12.010
Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70(7), 740-749. http://doi.org/10.1001/jamapsychiatry.2013.1273
Humphreys, K. L., Katz, S. J., Lee, S. S., Hammen, C., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent-child difficulties in two complementary samples. Journal of Abnormal Psychology, 122(3), 854-867. http://doi.org/10.1037/a0033895
Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54(6), 709-715. http://doi.org/10.1016/j.paid.2012.11.031
Olsavsky, A. K., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74(11), 853-860. http://doi.org/10.1016/j.biopsych.2013.05.025
Telzer, E. H., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33(33), 13484-13488. http://doi.org/10.1523/JNEUROSCI.1272-13.2013
Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race is not present in childhood but emerges over adolescence. Journal of Cognitive Neuroscience, 25(2), 234-244. http://doi.org/10.1162/jocn_a_00311
2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41(3), 370-377. http://doi.org/10.1080/15374416.2012.656557
Humphreys, K. L., Foley, K. M., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151. http://doi.org/10.1037/a0022644
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16(4), 267-275. http://doi.org/10.1177/1087054710387264
Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. G., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among Vietnam combat veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25(4), 416-425. http://doi.org/10.1002/jts.21729
Tottenham, N., Shapiro, M., Telzer, E. H., & Humphreys, K. L. (2012). Amygdala response to mother. Developmental Science, 15(3), 307-319. http://doi.org/10.1111/j.1467-7687.2011.01128.x
2011
Castel, A. D., Humphreys, K. L., Lee, S. S., Galván, A., Balota, D. A., & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47(6), 1553-1564. http://doi.org/10.1037/a0025623
Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25(1), 15-24. http://doi.org/10.1037/a0020298
Feinstein, B. A., Humphreys, K. L., Bovin, M. J., Marx, B. P., & Resick, P. A. (2011). Victim-offender relationship status moderates the relationships of peritraumatic emotional responses, active resistance, and posttraumatic stress symptomatology in female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3(2), 192-200. http://doi.org/10.1037/a0021652
Humphreys, K. L. & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. http://doi.org/10.1007/s10862-011-9237-6
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31(3), 328-341. http://doi.org/10.1016/j.cpr.2011.01.006
2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relationship to posttraumatic stress symptomatology. Journal of Interpersonal Violence, 25(2), 358-373. http://doi.org/10.1177/0886260509334412
Heflinger, C. A. & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of one state’s public service system. Psychological Services, 5, 139-152. http://doi.org/10.1037/1541-1559.5.2.139
Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Grove, W. M., Kaloupek, D. G., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196(8), 605-611. http://doi.org/10.1097/NMD.0b013e318181326d