Electronic copies of these publications are available for individual, non-commercial use only (†equal contribution)
2020 and in press
Humphreys, K. L., Camacho, M. C., Roth, M. C., & Estes, E. C. (2020). Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants. Developmental Cognitive Neuroscience, 46, 100877. https://doi.org/10.1016/j.dcn.2020.100877
King, L. S., Camacho, M. C., Humphreys, K. L., Montez, D. F., & Gotlib, I. H. (in press). Naturalistic language input is associated with resting-state functional connectivity in infancy. Journal of Neuroscience.
Cárdenas E. F., Kujawa, A., & Humphreys, K. L. (2020). Neurobiological changes during the peripartum period: Implications for health and behavior. Social Cognitive and Affective Neuroscience, 1097-1110. http://doi.org/10.1093/scan/nsz091
Colich, N. L., Sheridan, M. A., Humphreys, K. L., Wade, M., Tibu, F., Nelson, C. A., Zeanah, C. H., Fox, N. A., & McLaughlin, K. A. (in press). Heightened sensitivity to the caregiving environment during adolescence: Implications for recovery following early-life adversity. Journal of Child Psychology and Psychiatry. https://doi.org/10.1111/jcpp.13347
Humphreys, K. L. & Salo, V. C. (2020). Expectable environments in early life. Current Opinion in Behavioral Sciences, 36, 115-119. https://doi.org/10.1016/j.cobeha.2020.09.004
Humphreys, K. L., Guyon-Harris, K. L., Tibu, F., Wade, M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16. Journal of Consulting and Clinical Psychology.
Guyon-Harris, K. L., Humphreys, K. L., & Zeanah, C. H. (in press). Adverse caregiving in early life: The trauma and deprivation distinction in young children. Journal of Infant Mental Health. https://doi.org/10.1002/imhj.21892
Humphreys, K. L., Machlin, L. S., Guyon-Harris, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychosocial deprivation and receptive language: A two sample study. Journal of Neurodevelopmental Disorders.
Roth, M. C., Humphreys, K. L., King, L. S., Mondal, S., Gotlib, I. H., & Robackis, T. K. (2020). Attachment security in pregnancy mediates the association between maternal childhood maltreatment and emotional and behavioral problems in offspring. Child Psychiatry & Human Development. https://doi.org/10.1007/s10578-020-01073-7
Humphreys, K. L. (in press). Child maltreatment recurrence points to urgent need to improve systems for identification and prevention. Journal of the American Academy of Child and Adolescent Psychiatry. doi:10.1016/j.jaac.2020.07.005
Humphreys, K. L., Sisk, L. M., Mancszak, E. M., Lin, J., & Gotlib, I. H. (in press). Depressive symptoms predict change in telomere length and mitochondrial DNA copy number across adolescence. Journal of the American Academy of Child and Adolescent Psychiatry. http://doi.org/10.1016/j.jaac.2019.09.031
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Tibu, F., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2020). Early caregiving quality predicts consistency of competent functioning from middle childhood to adolescence following early psychosocial deprivation. Development and Psychopathology. https://doi.org/10.1017/S0954579419001500
King, L. S., Dennis, E. L., Humphreys, K. L., Thompson, P. M., & Gotlib, I. H. (2020). Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls. Developmental Cognitive Neuroscience, 44. http://doi.org/10.1016/j.dcn.2020.100796
Callaghan, B. L., Fields, A., Gee, D. G., Gabard-Durnam, L., Caldera, C., Humphreys, K. L., Goff, B., Flannery, J., Telzer, E. H., Shapiro, M., & Tottenham, N. (2020). Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, 32(1), 309-328. http://doi.org/10.1017/S0954579419000087
Castellanos, R., Spinel, M. Y., Phan, V., Orengo-Aguayo, R., Humphreys, K. L., & Flory, K. (2020). A systematic review and meta-analysis of cultural adaptations of mindfulness-based interventions for Hispanic populations. Mindfulness, 11, 317-332. http://doi.org/10.1007/s12671-019-01210-x
Gotlib, I. H., Goodman, S. H., & Humphreys, K. L. (2020). Studying the intergenerational transmission of risk for depression: Current status and future directions. Current Directions in Psychological Science, 29(2), 174-179. http://doi.org/10.1177/0963721420901590
Humphreys, K. L., Myint, M. T., & Zeanah, C. H. (2020). Increased risk for family violence during the COVID-19 pandemic. Pediatrics, 146(1), e20200982. http://doi.org/10.1542/peds.2020-0982
Humphreys, K. L., LeMoult, J., Wear, J. G., Piersiak, H. A., Lee, A., & Gotlib, I. H. (2020). Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse & Neglect, 102. http://doi.org/10.1016/j.chiabu.2020.104361
LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J., Ip, E., & Gotlib, I. H. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59(7), 842-855. http://doi.org/10.1016/j.jaac.2019.10.011
Miller, J. G., Ho, T. C., Humphreys, K. L., King, L. S., Foland-Ross, L. C., Colich, N. L., Ordaz, S. J., Lin, J., & Gotlib, I. H. (2020). Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation. Cerebral Cortex, 30(7), 4269-4280. http://doi.org/10.1093/cercor/bhaa057
Moore, S. R., Humphreys, K. L., Colich, N. L., Davis, E. G., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., & Gotlib, I. H. (2020). Distinctions between sex and time in patterns of DNA methylation across puberty. BMC Genomics, 21(1), 389. http://doi.org/10.1186/s12864-020-06789-3
Muscatell, K. A., Brosso, S. N., & Humphreys, K. L. (2020). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry, 25, 2189-2199. http://doi.org/10.1038/s41380-018-0259-2
Robakis, T. K., Zhang, S., Rasgon, N. L., Li, T., Wang, T., Roth, M. C., Humphreys, K. L., Gotlib, I. H., Ho, M., Khechaduri, A., Watson, K., Roat-Shumway, S., Budhan, V. V., David, K. N., Crowe, S. D., Williams, K. E., & Urban, A. E. (2020). Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Translational Psychiatry, 10(1), 48. http://doi.org/10.1038/s41398-020-0703-3
Salo, V. C., Schunck, S. J., & Humphreys, K. L. (2020). Depressive symptoms in parents are associated with reduced empathy toward their young children. PLoS ONE, 15(3), e0230636. http://doi.org/10.1371/journal.pone.0230636
Zeanah, C. H. & Humphreys, K. L. (2020). Global prevalence of institutional care for children: A call for change. The Lancet Child & Adolescent Health, 4(5), 343-344. http://doi.org/10.1016/S2352-4642(20)30055-9
2019
Callaghan, B. L., Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: An examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(7), 664-671. http://doi.org/10.1016/j.bpsc.2019.02.001
Camacho, M. C., King, L. S., Ojha, A., Garcia, C. M., Sisk, L. M., Cichocki, A. C., Humphreys, K. L., & Gotlib, I. H. (2019). Cerebral blood flow in 5- to 8-month-olds: Regional tissue maturity is associated with infant affect. Developmental Science, e12928. http://doi.org/10.1111/desc.12928
Dennis, E. L., Humphreys, K. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Irritability and brain volume in adolescents: Cross-sectional and longitudinal associations. Social Cognitive and Affective Neuroscience, 14(7), 687-698. http://doi.org/10.1093/scan/nsz053
Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development, 21(2), 95-110. http://doi.org/10.1080/14616734.2018.1499208
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse and Neglect, 88, 96-106. http://doi.org/10.1016/j.chiabu.2018.11.005
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Gleason, M. M., Nelson, C. A., Fox, N. A., Zeanah, C. H. (2019). Disinhibited social engagement disorder in early childhood predicts reduced competence in early adolescence. Journal of Abnormal Child Psychology, 47(10), 1735-1745. http://doi.org/10.1007/s10802-019-00547-0
Humphreys, K. L., Moore, S. R., Davis, E. G., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2019). DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: A prospective analysis. Translational Psychiatry, 9(1), 245. http://doi.org/10.1038/s41398-019-0582-7
Humphreys, K. L. (2019). Early caregiving intervention holds promise for long-term improvements in neural function following adversity. Biological Psychiatry, 85(4), e15-e16. http://doi.org/10.1016/j.biopsych.2018.12.005
Humphreys, K. L. (2019). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology, 48(1), 166-178. http://doi.org/10.1080/15374416.2018.1534209
Humphreys, K. L. (2019). Understanding the link between early adversity and disease – stress, immunity, and prevention. Brain, Behavior, and Immunity, 78, 1-2. http://doi.org/10.1016/j.bbi.2018.12.019
Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (2019). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science, 22(3), e12775. http://doi.org/10.1111/desc.12775
Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology, 47(3), 421-432. http://doi.org/10.1007/s10802-018-0443-5
Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (2019). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, 31(4), 1477-1487. http://doi.org/10.1017/S0954579418001050
Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2019). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology, 48(5), 781-789. http://doi.org/10.1080/15374416.2018.1460847
King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2019). A person-centered approach to the assessment of early life stress: Associations with the volume of stress-sensitive brain regions in early adolescence. Development and Psychopathology, 31(2), 643-655. http://doi.org/10.1017/S0954579418000184
King, L. S., Humphreys, K. L., & Gotlib, I. H. (2019). The neglect–enrichment continuum: Characterizing variation in early caregiving environments. Developmental Review, 51, 109-122. http://doi.org/10.1016/j.dr.2019.01.001
Kircanski, K., Sisk, L. M., Ho, T. C., Humphreys, K. L., King, L. S., Colich, N. L., Ordaz, S. J., & Gotlib, I. H. (2019). Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. Development and Psychopathology, 31(3), 1011-1022. http://doi.org/10.1017/S0954579419000555
LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2019). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology, 47(2), 199-207. http://doi.org/10.1007/s10802-018-0430-x
2018
Ellwood-Lowe, M. E., Humphreys, K. L., Ordaz, S. J., Camacho, M. C., Sacchet, M. D., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume
trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. http://doi.org/10.1016/j.dcn.2017.12.005
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57(5), 329-335. http://doi.org/10.1016/j.jaac.2018.02.009
Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. http://doi.org/10.1016/j.jad.2018.05.072
Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59(7), 811-821. http://doi.org/10.1111/jcpp.12865
Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24(2), 261-276. http://doi.org/10.1080/09297049.2016.1264578
Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. http://doi.org/10.1016/j.chiabu.2018.03.016
Zeanah, C. H. & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57(9), 637-644. http://doi.org/10.1016/j.jaac.2018.06.007
2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29(5), 1851-1864. http://doi.org/10.1017/S0954579417001444
Davis, E. G., Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2017). Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume. Translational Psychiatry, 7(8), e1223. http://doi.org/10.1038/tp.2017.188
Flannery, J. E., Gabard-Durnam, L. J., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E. H., Humphreys, K. L., Lumian, D. S., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166. http://doi.org/10.1016/j.dcn.2017.03.006
Galán, C. A. & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times, 34, 1-3.
Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience, 12(9), 1460-1469. http://doi.org/10.1093/scan/nsx065
Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29(2), 675-684. http://doi.org/10.1017/S0954579417000256
Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms. Journal of Clinical Child and Adolescent Psychology, 46(6), 903-914. http://doi.org/10.1080/15374416.2015.1094739
King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A. N., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroendocrinology, 77, 68-74. http://doi.org/10.1016/j.psyneuen.2016.11.024
VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017).
Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and Psychopathology, 29(2), 519-533. http://doi.org/10.1017/S0954579417000153
Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children: Insights from the Bucharest Early Intervention Project. Current Opinion in Psychology, 15, 182-188. http://doi.org/10.1016/j.copsyc.2017.02.024
2016
Gabard-Durnam, L. J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K. L., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36(17), 4771-4784. http://doi.org/10.1523/JNEUROSCI.0598-16.2016
Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37(5), 476-485. http://doi.org/10.1002/imhj.21592
Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L., Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57(10), 1135-1144. http://doi.org/10.1111/jcpp.12578
Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. http://doi.org/10.1016/j.psychres.2016.09.023
Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44(5), 1023-1032. http://doi.org/10.1007/s10802-015-0095-7
Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57(10), 1174-1182. http://doi.org/10.1111/jcpp.12607
Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16(1), 101-109. http://doi.org/10.1037/emo0000116
Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161(1), 84-93. http://doi.org/10.1002/ajpa.23010
Silvers, J. A., Lumian, D. S., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D. S., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala-hippocampal-PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36(24), 6420-6430. http://doi.org/10.1523/JNEUROSCI.0038-16.2016
Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. Journal of Attention Disorders, 20(8), 695-703. http://doi.org/10.1177/1087054712465337
2015
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Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis. Clinical Child and Family Psychology Review, 18(1), 50-76. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27(2), 347-367. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Sheridan, M., Humphreys, K., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2015). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39(2), 150-160. http://doi.org/10.1177/0165025414538557
Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter genotype (5HTTLPR) moderates
the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36(6), 409-416. http://doi.org/10.1017/S0954579414001266
Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: Follow-up of an open, randomised controlled trial. The Lancet Psychiatry, 2(7), 625-634. http://doi.org/10.1016/S2215-0366(15)00095-4
Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration-exploitation strategy is dependent on early experience. Developmental Psychobiology, 57(3), 313-321. http://doi.org/10.1002/dev.21293
Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54(12), 977-983. http://doi.org/10.1016/j.jaac.2015.09.010
Humphreys, K. L. & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40(1), 154-170. http://doi.org/10.1038/npp.2014.165
Telzer, E. H., Flannery, J., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. G., & Tottenham, N. (2015). "The cooties effect": Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 27(9), 1685-1696. http://doi.org/10.1162/jocn_a_00813
2014
Gabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 years: A cross-sectional study. NeuroImage, 95, 193-207. http://doi.org/10.1016/j.neuroimage.2014.03.038
Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala-prefrontal circuitry during childhood but not during adolescence. Psychological Science, 25(11), 2067-2078. http://doi.org/10.1177/0956797614550878
Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of Catechol-O-methyltransferase genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24(8), 454-457. http://doi.org/10.1089/cap.2014.0077
Lee, S. S. & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children. Experimental and Clinical Psychopharmacology, 22(2), 100-109. http://doi.org/10.1037/a0035338
Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19(3-4), 145-155. http://doi.org/10.1177/1077559514543827
Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Mental Health Journal, 35(2), 123-131. http://doi.org/10.1002/imhj.21428
2013
Gee, D. G., Gabard-Durnam, L. J., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E. H., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110(39), 15638-15643. http://doi.org/10.1073/pnas.1307893110
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33(10), 4584-4593. http://doi.org/10.1523/JNEUROSCI.3446-12.2013
Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. http://doi.org/10.1016/j.neuroscience.2012.12.010
Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70(7), 740-749. http://doi.org/10.1001/jamapsychiatry.2013.1273
Humphreys, K. L., Katz, S. J., Lee, S. S., Hammen, C., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent-child difficulties in two complementary samples. Journal of Abnormal Psychology, 122(3), 854-867. http://doi.org/10.1037/a0033895
Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54(6), 709-715. http://doi.org/10.1016/j.paid.2012.11.031
Olsavsky, A. K., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74(11), 853-860. http://doi.org/10.1016/j.biopsych.2013.05.025
Telzer, E. H., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33(33), 13484-13488. http://doi.org/10.1523/JNEUROSCI.1272-13.2013
Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race is not present in childhood but emerges over adolescence. Journal of Cognitive Neuroscience, 25(2), 234-244. http://doi.org/10.1162/jocn_a_00311
2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41(3), 370-377. http://doi.org/10.1080/15374416.2012.656557
Humphreys, K. L., Foley, K. M., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151. http://doi.org/10.1037/a0022644
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16(4), 267-275. http://doi.org/10.1177/1087054710387264
Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. G., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among Vietnam combat veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25(4), 416-425. http://doi.org/10.1002/jts.21729
Tottenham, N., Shapiro, M., Telzer, E. H., & Humphreys, K. L. (2012). Amygdala response to mother. Developmental Science, 15(3), 307-319. http://doi.org/10.1111/j.1467-7687.2011.01128.x
2011
Castel, A. D., Humphreys, K. L., Lee, S. S., Galván, A., Balota, D. A., & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47(6), 1553-1564. http://doi.org/10.1037/a0025623
Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25(1), 15-24. http://doi.org/10.1037/a0020298
Feinstein, B. A., Humphreys, K. L., Bovin, M. J., Marx, B. P., & Resick, P. A. (2011). Victim-offender relationship status moderates the relationships of peritraumatic emotional responses, active resistance, and posttraumatic stress symptomatology in female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3(2), 192-200. http://doi.org/10.1037/a0021652
Humphreys, K. L. & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. http://doi.org/10.1007/s10862-011-9237-6
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31(3), 328-341. http://doi.org/10.1016/j.cpr.2011.01.006
2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relationship to posttraumatic stress symptomatology. Journal of Interpersonal Violence, 25(2), 358-373. http://doi.org/10.1177/0886260509334412
Heflinger, C. A. & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of one state’s public service system. Psychological Services, 5, 139-152. http://doi.org/10.1037/1541-1559.5.2.139
Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Grove, W. M., Kaloupek, D. G., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196(8), 605-611. http://doi.org/10.1097/NMD.0b013e318181326d
2020 and in press
Humphreys, K. L., Camacho, M. C., Roth, M. C., & Estes, E. C. (2020). Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants. Developmental Cognitive Neuroscience, 46, 100877. https://doi.org/10.1016/j.dcn.2020.100877
King, L. S., Camacho, M. C., Humphreys, K. L., Montez, D. F., & Gotlib, I. H. (in press). Naturalistic language input is associated with resting-state functional connectivity in infancy. Journal of Neuroscience.
Cárdenas E. F., Kujawa, A., & Humphreys, K. L. (2020). Neurobiological changes during the peripartum period: Implications for health and behavior. Social Cognitive and Affective Neuroscience, 1097-1110. http://doi.org/10.1093/scan/nsz091
Colich, N. L., Sheridan, M. A., Humphreys, K. L., Wade, M., Tibu, F., Nelson, C. A., Zeanah, C. H., Fox, N. A., & McLaughlin, K. A. (in press). Heightened sensitivity to the caregiving environment during adolescence: Implications for recovery following early-life adversity. Journal of Child Psychology and Psychiatry. https://doi.org/10.1111/jcpp.13347
Humphreys, K. L. & Salo, V. C. (2020). Expectable environments in early life. Current Opinion in Behavioral Sciences, 36, 115-119. https://doi.org/10.1016/j.cobeha.2020.09.004
Humphreys, K. L., Guyon-Harris, K. L., Tibu, F., Wade, M., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16. Journal of Consulting and Clinical Psychology.
Guyon-Harris, K. L., Humphreys, K. L., & Zeanah, C. H. (in press). Adverse caregiving in early life: The trauma and deprivation distinction in young children. Journal of Infant Mental Health. https://doi.org/10.1002/imhj.21892
Humphreys, K. L., Machlin, L. S., Guyon-Harris, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (in press). Psychosocial deprivation and receptive language: A two sample study. Journal of Neurodevelopmental Disorders.
Roth, M. C., Humphreys, K. L., King, L. S., Mondal, S., Gotlib, I. H., & Robackis, T. K. (2020). Attachment security in pregnancy mediates the association between maternal childhood maltreatment and emotional and behavioral problems in offspring. Child Psychiatry & Human Development. https://doi.org/10.1007/s10578-020-01073-7
Humphreys, K. L. (in press). Child maltreatment recurrence points to urgent need to improve systems for identification and prevention. Journal of the American Academy of Child and Adolescent Psychiatry. doi:10.1016/j.jaac.2020.07.005
Humphreys, K. L., Sisk, L. M., Mancszak, E. M., Lin, J., & Gotlib, I. H. (in press). Depressive symptoms predict change in telomere length and mitochondrial DNA copy number across adolescence. Journal of the American Academy of Child and Adolescent Psychiatry. http://doi.org/10.1016/j.jaac.2019.09.031
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Tibu, F., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2020). Early caregiving quality predicts consistency of competent functioning from middle childhood to adolescence following early psychosocial deprivation. Development and Psychopathology. https://doi.org/10.1017/S0954579419001500
King, L. S., Dennis, E. L., Humphreys, K. L., Thompson, P. M., & Gotlib, I. H. (2020). Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls. Developmental Cognitive Neuroscience, 44. http://doi.org/10.1016/j.dcn.2020.100796
Callaghan, B. L., Fields, A., Gee, D. G., Gabard-Durnam, L., Caldera, C., Humphreys, K. L., Goff, B., Flannery, J., Telzer, E. H., Shapiro, M., & Tottenham, N. (2020). Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity. Development and Psychopathology, 32(1), 309-328. http://doi.org/10.1017/S0954579419000087
Castellanos, R., Spinel, M. Y., Phan, V., Orengo-Aguayo, R., Humphreys, K. L., & Flory, K. (2020). A systematic review and meta-analysis of cultural adaptations of mindfulness-based interventions for Hispanic populations. Mindfulness, 11, 317-332. http://doi.org/10.1007/s12671-019-01210-x
Gotlib, I. H., Goodman, S. H., & Humphreys, K. L. (2020). Studying the intergenerational transmission of risk for depression: Current status and future directions. Current Directions in Psychological Science, 29(2), 174-179. http://doi.org/10.1177/0963721420901590
Humphreys, K. L., Myint, M. T., & Zeanah, C. H. (2020). Increased risk for family violence during the COVID-19 pandemic. Pediatrics, 146(1), e20200982. http://doi.org/10.1542/peds.2020-0982
Humphreys, K. L., LeMoult, J., Wear, J. G., Piersiak, H. A., Lee, A., & Gotlib, I. H. (2020). Child maltreatment and depression: A meta-analysis of studies using the Childhood Trauma Questionnaire. Child Abuse & Neglect, 102. http://doi.org/10.1016/j.chiabu.2020.104361
LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J., Ip, E., & Gotlib, I. H. (2020). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 59(7), 842-855. http://doi.org/10.1016/j.jaac.2019.10.011
Miller, J. G., Ho, T. C., Humphreys, K. L., King, L. S., Foland-Ross, L. C., Colich, N. L., Ordaz, S. J., Lin, J., & Gotlib, I. H. (2020). Early life stress, frontoamygdala connectivity, and biological aging in adolescence: A longitudinal investigation. Cerebral Cortex, 30(7), 4269-4280. http://doi.org/10.1093/cercor/bhaa057
Moore, S. R., Humphreys, K. L., Colich, N. L., Davis, E. G., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., & Gotlib, I. H. (2020). Distinctions between sex and time in patterns of DNA methylation across puberty. BMC Genomics, 21(1), 389. http://doi.org/10.1186/s12864-020-06789-3
Muscatell, K. A., Brosso, S. N., & Humphreys, K. L. (2020). Socioeconomic status and inflammation: A meta-analysis. Molecular Psychiatry, 25, 2189-2199. http://doi.org/10.1038/s41380-018-0259-2
Robakis, T. K., Zhang, S., Rasgon, N. L., Li, T., Wang, T., Roth, M. C., Humphreys, K. L., Gotlib, I. H., Ho, M., Khechaduri, A., Watson, K., Roat-Shumway, S., Budhan, V. V., David, K. N., Crowe, S. D., Williams, K. E., & Urban, A. E. (2020). Epigenetic signatures of attachment insecurity and childhood adversity provide evidence for role transition in the pathogenesis of perinatal depression. Translational Psychiatry, 10(1), 48. http://doi.org/10.1038/s41398-020-0703-3
Salo, V. C., Schunck, S. J., & Humphreys, K. L. (2020). Depressive symptoms in parents are associated with reduced empathy toward their young children. PLoS ONE, 15(3), e0230636. http://doi.org/10.1371/journal.pone.0230636
Zeanah, C. H. & Humphreys, K. L. (2020). Global prevalence of institutional care for children: A call for change. The Lancet Child & Adolescent Health, 4(5), 343-344. http://doi.org/10.1016/S2352-4642(20)30055-9
2019
Callaghan, B. L., Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2019). Decreased amygdala reactivity to parent cues protects against anxiety following early adversity: An examination across 3 years. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(7), 664-671. http://doi.org/10.1016/j.bpsc.2019.02.001
Camacho, M. C., King, L. S., Ojha, A., Garcia, C. M., Sisk, L. M., Cichocki, A. C., Humphreys, K. L., & Gotlib, I. H. (2019). Cerebral blood flow in 5- to 8-month-olds: Regional tissue maturity is associated with infant affect. Developmental Science, e12928. http://doi.org/10.1111/desc.12928
Dennis, E. L., Humphreys, K. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Irritability and brain volume in adolescents: Cross-sectional and longitudinal associations. Social Cognitive and Affective Neuroscience, 14(7), 687-698. http://doi.org/10.1093/scan/nsz053
Guyon-Harris, K. L., Humphreys, K. L., Degnan, K., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). A prospective longitudinal study of reactive attachment disorder following early institutional care: Considering variable- and person-centered approaches. Attachment and Human Development, 21(2), 95-110. http://doi.org/10.1080/14616734.2018.1499208
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2019). Signs of attachment disorders and social functioning among early adolescents with a history of institutional care. Child Abuse and Neglect, 88, 96-106. http://doi.org/10.1016/j.chiabu.2018.11.005
Guyon-Harris, K. L., Humphreys, K. L., Miron, D., Gleason, M. M., Nelson, C. A., Fox, N. A., Zeanah, C. H. (2019). Disinhibited social engagement disorder in early childhood predicts reduced competence in early adolescence. Journal of Abnormal Child Psychology, 47(10), 1735-1745. http://doi.org/10.1007/s10802-019-00547-0
Humphreys, K. L., Moore, S. R., Davis, E. G., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2019). DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: A prospective analysis. Translational Psychiatry, 9(1), 245. http://doi.org/10.1038/s41398-019-0582-7
Humphreys, K. L. (2019). Early caregiving intervention holds promise for long-term improvements in neural function following adversity. Biological Psychiatry, 85(4), e15-e16. http://doi.org/10.1016/j.biopsych.2018.12.005
Humphreys, K. L. (2019). Future directions in the study and treatment of parent–child separation. Journal of Clinical Child and Adolescent Psychology, 48(1), 166-178. http://doi.org/10.1080/15374416.2018.1534209
Humphreys, K. L. (2019). Understanding the link between early adversity and disease – stress, immunity, and prevention. Brain, Behavior, and Immunity, 78, 1-2. http://doi.org/10.1016/j.bbi.2018.12.019
Humphreys, K. L., King, L. S., Sacchet, M. D., Camacho, M. C., Colich, N. L., Ordaz, S. J., Ho, T. C., & Gotlib, I. H. (2019). Evidence for a sensitive period in the effects of early life stress on hippocampal volume. Developmental Science, 22(3), e12775. http://doi.org/10.1111/desc.12775
Humphreys, K. L., Watts, E. L., Dennis, E. L., King, L. S., Thompson, P. M., & Gotlib, I. H. (2019). Stressful life events, ADHD symptoms, and brain structure in early adolescence. Journal of Abnormal Child Psychology, 47(3), 421-432. http://doi.org/10.1007/s10802-018-0443-5
Humphreys, K. L., Gabard-Durnam, L., Goff, B., Telzer, E. H., Flannery, J., Gee, D. G., Park, V., Lee, S. S., & Tottenham, N. (2019). Friendship and social functioning following early institutional rearing: The role of ADHD symptoms. Development and Psychopathology, 31(4), 1477-1487. http://doi.org/10.1017/S0954579418001050
Humphreys, K. L., Schouboe, S. N. F., Kircanski, K., Leibenluft, E., Stringaris, A., & Gotlib, I. H. (2019). Irritability, externalizing, and internalizing psychopathology in adolescence: Cross-sectional and longitudinal associations and moderation by sex. Journal of Clinical Child and Adolescent Psychology, 48(5), 781-789. http://doi.org/10.1080/15374416.2018.1460847
King, L. S., Humphreys, K. L., Camacho, M. C., & Gotlib, I. H. (2019). A person-centered approach to the assessment of early life stress: Associations with the volume of stress-sensitive brain regions in early adolescence. Development and Psychopathology, 31(2), 643-655. http://doi.org/10.1017/S0954579418000184
King, L. S., Humphreys, K. L., & Gotlib, I. H. (2019). The neglect–enrichment continuum: Characterizing variation in early caregiving environments. Developmental Review, 51, 109-122. http://doi.org/10.1016/j.dr.2019.01.001
Kircanski, K., Sisk, L. M., Ho, T. C., Humphreys, K. L., King, L. S., Colich, N. L., Ordaz, S. J., & Gotlib, I. H. (2019). Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. Development and Psychopathology, 31(3), 1011-1022. http://doi.org/10.1017/S0954579419000555
LeMoult, J., Humphreys, K. L., King, L. S., Colich, N. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2019). Associations among early life stress, rumination, symptoms of psychopathology, and sex in youth in the early stages of puberty: A moderated mediation analysis. Journal of Abnormal Child Psychology, 47(2), 199-207. http://doi.org/10.1007/s10802-018-0430-x
2018
Ellwood-Lowe, M. E., Humphreys, K. L., Ordaz, S. J., Camacho, M. C., Sacchet, M. D., & Gotlib, I. H. (2018). Time-varying effects of income on hippocampal volume
trajectories in adolescent girls. Developmental Cognitive Neuroscience, 30, 41-50. http://doi.org/10.1016/j.dcn.2017.12.005
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2018). Course of disinhibited social engagement disorder from early childhood to early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 57(5), 329-335. http://doi.org/10.1016/j.jaac.2018.02.009
Humphreys, K. L., King, L. S., Choi, P., & Gotlib, I. H. (2018). Maternal depressive symptoms, self-focus, and caregiving behavior. Journal of Affective Disorders, 238, 465-471. http://doi.org/10.1016/j.jad.2018.05.072
Humphreys, K. L., Miron, D., McLaughlin, K. A., Sheridan, M. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2018). Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation. Journal of Child Psychology and Psychiatry, 59(7), 811-821. http://doi.org/10.1111/jcpp.12865
Humphreys, K. L., Tottenham, N., & Lee, S. S. (2018). Risky decision-making in children with and without ADHD: A prospective study. Child Neuropsychology, 24(2), 261-276. http://doi.org/10.1080/09297049.2016.1264578
Roth, M. C., Humphreys, K. L., King, L. S., & Gotlib, I. H. (2018). Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys. Child Abuse & Neglect, 80, 80-89. http://doi.org/10.1016/j.chiabu.2018.03.016
Zeanah, C. H. & Humphreys, K. L. (2018). Child abuse and neglect. Journal of the American Academy of Child and Adolescent Psychiatry, 57(9), 637-644. http://doi.org/10.1016/j.jaac.2018.06.007
2017
Colich, N. L., Williams, E. S., Ho, T. C., King, L. S., Humphreys, K. L., Price, A. N., Ordaz, S. J., & Gotlib, I. H. (2017). The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. Development and Psychopathology, 29(5), 1851-1864. http://doi.org/10.1017/S0954579417001444
Davis, E. G., Humphreys, K. L., McEwen, L. M., Sacchet, M. D., Camacho, M. C., MacIsaac, J. L., Lin, D. T. S., Kobor, M. S., & Gotlib, I. H. (2017). Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume. Translational Psychiatry, 7(8), e1223. http://doi.org/10.1038/tp.2017.188
Flannery, J. E., Gabard-Durnam, L. J., Shapiro, M., Goff, B., Caldera, C., Louie, J., Gee, D. G., Telzer, E. H., Humphreys, K. L., Lumian, D. S., & Tottenham, N. (2017). Diurnal cortisol after early institutional care - Age matters. Developmental Cognitive Neuroscience, 25, 160-166. http://doi.org/10.1016/j.dcn.2017.03.006
Galán, C. A. & Humphreys, K. L. (2017). ADHD and substance use: Current evidence and treatment considerations. Psychiatric Times, 34, 1-3.
Ho, T. C., King, L. S., Leong, J. K., Colich, N. L., Humphreys, K. L., Ordaz, S. J., & Gotlib, I. H. (2017). Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. Social Cognitive and Affective Neuroscience, 12(9), 1460-1469. http://doi.org/10.1093/scan/nsx065
Humphreys, K. L., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2017). Signs of reactive attachment disorder and disinhibited social engagement disorder at age 12 years: Effects of institutional care history and high-quality foster care. Development and Psychopathology, 29(2), 675-684. http://doi.org/10.1017/S0954579417000256
Humphreys, K. L., Weems, C. F., & Scheeringa, M. S. (2017). The role of anxiety control and treatment implications of informant agreement on child PTSD symptoms. Journal of Clinical Child and Adolescent Psychology, 46(6), 903-914. http://doi.org/10.1080/15374416.2015.1094739
King, L. S., Colich, N. L., LeMoult, J., Humphreys, K. L., Ordaz, S. J., Price, A. N., & Gotlib, I. H. (2017). The impact of the severity of early life stress on diurnal cortisol: The role of puberty. Psychoneuroendocrinology, 77, 68-74. http://doi.org/10.1016/j.psyneuen.2016.11.024
VanTieghem, M. R., Gabard-Durnam, L., Goff, B., Flannery, J., Humphreys, K. L., Telzer, E. H., Caldera, C., Louie, J. Y., Shapiro, M., Bolger, N., & Tottenham, N. (2017).
Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms. Development and Psychopathology, 29(2), 519-533. http://doi.org/10.1017/S0954579417000153
Zeanah, C. H., Humphreys, K. L., Fox, N. A., & Nelson, C. A. (2017). Alternatives for abandoned children: Insights from the Bucharest Early Intervention Project. Current Opinion in Psychology, 15, 182-188. http://doi.org/10.1016/j.copsyc.2017.02.024
2016
Gabard-Durnam, L. J., Gee, D. G., Goff, B., Flannery, J., Telzer, E., Humphreys, K. L., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2016). Stimulus-elicited connectivity influences resting-state connectivity years later in human development: A prospective study. Journal of Neuroscience, 36(17), 4771-4784. http://doi.org/10.1523/JNEUROSCI.0598-16.2016
Gleason, M. M. & Humphreys, K. L. (2016). Categorical diagnosis of extreme hyperactivity, impulsivity, and inattention in very young children. Infant Mental Health Journal, 37(5), 476-485. http://doi.org/10.1002/imhj.21592
Green, S. A., Goff, B., Gee, D. G., Gabard-Durnam, L., Flannery, J., Telzer, E. H., Humphreys, K. L., Louie, J., & Tottenham, N. (2016). Discrimination of amygdala response predicts future separation anxiety in youth with early deprivation. Journal of Child Psychology and Psychiatry, 57(10), 1135-1144. http://doi.org/10.1111/jcpp.12578
Humphreys, K. L., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level. Psychiatry Research, 246, 95-100. http://doi.org/10.1016/j.psychres.2016.09.023
Humphreys, K. L., Galán, C. A., Tottenham, N., & Lee, S. S. (2016). Impaired social decision-making mediates the association between ADHD and social problems. Journal of Abnormal Child Psychology, 44(5), 1023-1032. http://doi.org/10.1007/s10802-015-0095-7
Humphreys, K. L., Kircanski, K., Colich, N. L., & Gotlib, I. H. (2016). Attentional avoidance of fearful facial expressions following early life stress is associated with impaired social functioning. Journal of Child Psychology and Psychiatry, 57(10), 1174-1182. http://doi.org/10.1111/jcpp.12607
Humphreys, K. L., Telzer, E. H., Flannery, J., Goff, B., Gabard-Durnam, L., Gee, D. G., Lee, S. S., & Tottenham, N. (2016). Risky decision making from childhood through adulthood: Contributions of learning and sensitivity to negative feedback. Emotion, 16(1), 101-109. http://doi.org/10.1037/emo0000116
Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016). DNA methylation at stress-related genes is associated with exposure to early life institutionalization. American Journal of Physical Anthropology, 161(1), 84-93. http://doi.org/10.1002/ajpa.23010
Silvers, J. A., Lumian, D. S., Gabard-Durnam, L., Gee, D. G., Goff, B., Fareri, D. S., Caldera, C., Flannery, J., Telzer, E. H., Humphreys, K. L., & Tottenham, N. (2016). Previous institutionalization is followed by broader amygdala-hippocampal-PFC network connectivity during aversive learning in human development. Journal of Neuroscience, 36(24), 6420-6430. http://doi.org/10.1523/JNEUROSCI.0038-16.2016
Singer, M. J., Humphreys, K. L., & Lee, S. S. (2016). Coping self-efficacy mediates the association between child abuse and ADHD in adulthood. Journal of Attention Disorders, 20(8), 695-703. http://doi.org/10.1177/1087054712465337
2015
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Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015). Misuse of stimulant medication among college students: A comprehensive review and meta-analysis. Clinical Child and Family Psychology Review, 18(1), 50-76. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Humphreys, K. L., Fleming, A. S., Kraemer, G. W., & Drury, S. S. (2015). Using cross-species comparisons and a neurobiological framework to understand early social deprivation effects on behavioral development. Development and Psychopathology, 27(2), 347-367. http://doi.org/10.1007/s10567-014-0177-z
Brett, Z. H., Sheridan, M., Humphreys, K., Smyke, A., Gleason, M. M., Fox, N., Zeanah, C., Nelson, C., & Drury, S. (2015). A neurogenetics approach to defining differential susceptibility to institutional care. International Journal of Behavioral Development, 39(2), 150-160. http://doi.org/10.1177/0165025414538557
Humphreys, K. L., Zeanah, C. H., Nelson, C. A., Fox, N. A., & Drury, S. S. (2015). Serotonin transporter genotype (5HTTLPR) moderates
the longitudinal impact of atypical attachment on externalizing behavior. Journal of Developmental and Behavioral Pediatrics, 36(6), 409-416. http://doi.org/10.1017/S0954579414001266
Humphreys, K. L., Gleason, M. M., Drury, S. S., Miron, D., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2015). Effects of institutional rearing and foster care on psychopathology at age 12 years in Romania: Follow-up of an open, randomised controlled trial. The Lancet Psychiatry, 2(7), 625-634. http://doi.org/10.1016/S2215-0366(15)00095-4
Humphreys, K. L., Lee, S. S., Telzer, E. H., Gabard-Durnam, L. J., Goff, B., Flannery, J., & Tottenham, N. (2015). Exploration-exploitation strategy is dependent on early experience. Developmental Psychobiology, 57(3), 313-321. http://doi.org/10.1002/dev.21293
Humphreys, K. L., McGoron, L., Sheridan, M. A., McLaughlin, K. A., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2015). High-quality foster care mitigates callous-unemotional traits following early deprivation in boys: A randomized controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 54(12), 977-983. http://doi.org/10.1016/j.jaac.2015.09.010
Humphreys, K. L. & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology Reviews, 40(1), 154-170. http://doi.org/10.1038/npp.2014.165
Telzer, E. H., Flannery, J., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. G., & Tottenham, N. (2015). "The cooties effect": Amygdala reactivity to opposite- versus same-sex faces declines from childhood to adolescence. Journal of Cognitive Neuroscience, 27(9), 1685-1696. http://doi.org/10.1162/jocn_a_00813
2014
Gabard-Durnam, L. J., Flannery, J., Goff, B., Gee, D. G., Humphreys, K. L., Telzer, E., Hare, T., & Tottenham, N. (2014). The development of human amygdala functional connectivity at rest from 4 to 23 years: A cross-sectional study. NeuroImage, 95, 193-207. http://doi.org/10.1016/j.neuroimage.2014.03.038
Gee, D. G., Gabard-Durnam, L., Telzer, E. H., Humphreys, K. L., Goff, B., Shapiro, M., Flannery, J., Lumian, D. S., Fareri, D. S., Caldera, C., & Tottenham, N. (2014). Maternal buffering of human amygdala-prefrontal circuitry during childhood but not during adolescence. Psychological Science, 25(11), 2067-2078. http://doi.org/10.1177/0956797614550878
Humphreys, K. L., Scheeringa, M. S., & Drury, S. S. (2014). Race moderates the association of Catechol-O-methyltransferase genotype and posttraumatic stress disorder in preschool children. Journal of Child and Adolescent Psychopharmacology, 24(8), 454-457. http://doi.org/10.1089/cap.2014.0077
Lee, S. S. & Humphreys, K. L. (2014). Interactive association of dopamine receptor (DRD4) genotype and ADHD on alcohol expectancies in children. Experimental and Clinical Psychopharmacology, 22(2), 100-109. http://doi.org/10.1037/a0035338
Sujan, A. C., Humphreys, K. L., Ray, L. A., & Lee, S. S. (2014). Differential association of child abuse with self-reported versus laboratory-based impulsivity and risk-taking in young adulthood. Child Maltreatment, 19(3-4), 145-155. http://doi.org/10.1177/1077559514543827
Tibu, F., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H. (2014). Psychopathology in young children in two types of foster care following institutional rearing. Infant Mental Health Journal, 35(2), 123-131. http://doi.org/10.1002/imhj.21428
2013
Gee, D. G., Gabard-Durnam, L. J., Flannery, J., Goff, B., Humphreys, K. L., Telzer, E. H., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation. Proceedings for the National Academy of Sciences USA, 110(39), 15638-15643. http://doi.org/10.1073/pnas.1307893110
Gee, D. G., Humphreys, K. L., Flannery, J., Goff, B., Telzer, E. H., Shapiro, M., Hare, T. A., Bookheimer, S. Y., & Tottenham, N. (2013). A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry. Journal of Neuroscience, 33(10), 4584-4593. http://doi.org/10.1523/JNEUROSCI.3446-12.2013
Goff, B., Gee, D. G., Telzer, E. H., Humphreys, K. L., Gabard-Durnam, L., Flannery, J., & Tottenham, N. (2013). Reduced nucleus accumbens reactivity and adolescent depression following early-life stress. Neuroscience, 249, 129-138. http://doi.org/10.1016/j.neuroscience.2012.12.010
Humphreys, K. L., Eng, T., & Lee, S. S. (2013). Stimulant medication and substance use outcomes: A meta-analysis. JAMA Psychiatry, 70(7), 740-749. http://doi.org/10.1001/jamapsychiatry.2013.1273
Humphreys, K. L., Katz, S. J., Lee, S. S., Hammen, C., Brennan, P. A., & Najman, J. M. (2013). The association of ADHD and depression: Mediation by peer problems and parent-child difficulties in two complementary samples. Journal of Abnormal Psychology, 122(3), 854-867. http://doi.org/10.1037/a0033895
Humphreys, K. L., Lee, S. S., & Tottenham, N. (2013). Not all risk taking behavior is bad: Associative sensitivity predicts learning during risk taking among high sensation seekers. Personality and Individual Differences, 54(6), 709-715. http://doi.org/10.1016/j.paid.2012.11.031
Olsavsky, A. K., Telzer, E. H., Shapiro, M., Humphreys, K. L., Flannery, J., Goff, B., & Tottenham, N. (2013). Indiscriminate amygdala response to mothers and strangers after early maternal deprivation. Biological Psychiatry, 74(11), 853-860. http://doi.org/10.1016/j.biopsych.2013.05.025
Telzer, E. H., Flannery, J., Shapiro, M., Humphreys, K. L., Goff, B., Gabard-Durnam, L., Gee, D. D., & Tottenham, N. (2013). Early experience shapes amygdala sensitivity to race: An international adoption design. Journal of Neuroscience, 33(33), 13484-13488. http://doi.org/10.1523/JNEUROSCI.1272-13.2013
Telzer, E. H., Humphreys, K. L., Shapiro, M., & Tottenham, N. (2013). Amygdala sensitivity to race is not present in childhood but emerges over adolescence. Journal of Cognitive Neuroscience, 25(2), 234-244. http://doi.org/10.1162/jocn_a_00311
2012
Humphreys, K. L., Aguirre, V. P., & Lee, S. S. (2012). Association of anxiety and ODD/CD in children with and without ADHD. Journal of Clinical Child and Adolescent Psychology, 41(3), 370-377. http://doi.org/10.1080/15374416.2012.656557
Humphreys, K. L., Foley, K. M., Feinstein, B. A., Marx, B. P., Kaloupek, D. G., & Keane, T. M. (2012). The influence of externalizing comorbidity on psychophysiological reactivity among veterans with posttraumatic stress disorder. Psychological Trauma: Theory, Research, Practice, and Policy, 4, 145-151. http://doi.org/10.1037/a0022644
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16(4), 267-275. http://doi.org/10.1177/1087054710387264
Marx, B. P., Bovin, M. J., Suvak, M. K., Monson, C. M., Sloan, D. M., Fredman, S. J., Humphreys, K. L., Kaloupek, D. G., & Keane, T. M. (2012). Concordance between physiological arousal and subjective distress among Vietnam combat veterans undergoing challenge testing for PTSD. Journal of Traumatic Stress, 25(4), 416-425. http://doi.org/10.1002/jts.21729
Tottenham, N., Shapiro, M., Telzer, E. H., & Humphreys, K. L. (2012). Amygdala response to mother. Developmental Science, 15(3), 307-319. http://doi.org/10.1111/j.1467-7687.2011.01128.x
2011
Castel, A. D., Humphreys, K. L., Lee, S. S., Galván, A., Balota, D. A., & McCabe, D. P. (2011). The development of memory efficiency and value-directed remembering across the life span: A cross-sectional study of memory and selectivity. Developmental Psychology, 47(6), 1553-1564. http://doi.org/10.1037/a0025623
Castel, A. D., Lee, S. S., Humphreys, K. L., & Moore, A. N. (2011). Memory capacity, selective control, and value-directed remembering in children with and without attention-deficit/hyperactivity disorder (ADHD). Neuropsychology, 25(1), 15-24. http://doi.org/10.1037/a0020298
Feinstein, B. A., Humphreys, K. L., Bovin, M. J., Marx, B. P., & Resick, P. A. (2011). Victim-offender relationship status moderates the relationships of peritraumatic emotional responses, active resistance, and posttraumatic stress symptomatology in female rape survivors. Psychological Trauma: Theory, Research, Practice, and Policy, 3(2), 192-200. http://doi.org/10.1037/a0021652
Humphreys, K. L. & Lee, S. S. (2011). Risk taking and sensitivity to punishment in children with ADHD, ODD, ADHD+ODD, and controls. Journal of Psychopathology and Behavioral Assessment, 33, 299-307. http://doi.org/10.1007/s10862-011-9237-6
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: A meta-analytic review. Clinical Psychology Review, 31(3), 328-341. http://doi.org/10.1016/j.cpr.2011.01.006
2008-2010
Humphreys, K. L., Sauder, C. L., Martin, E. K., & Marx, B. P. (2010). Tonic immobility in childhood sexual abuse survivors and its relationship to posttraumatic stress symptomatology. Journal of Interpersonal Violence, 25(2), 358-373. http://doi.org/10.1177/0886260509334412
Heflinger, C. A. & Humphreys, K. L. (2008). Identification and treatment of children with oppositional defiant disorder: A case study of one state’s public service system. Psychological Services, 5, 139-152. http://doi.org/10.1037/1541-1559.5.2.139
Marx, B. P., Humphreys, K. L., Weathers, F. W., Martin, E. K., Sloan, D. M., Grove, W. M., Kaloupek, D. G., & Keane, T. M. (2008). Development and initial validation of a statistical prediction instrument for assessing combat-related posttraumatic stress disorder. Journal of Nervous and Mental Disease, 196(8), 605-611. http://doi.org/10.1097/NMD.0b013e318181326d